Non-inferiority trials

Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration. Such studies are called non-inferiority (NI) trials. In this article, we look at so...

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Bibliographic Details
Published in:Perspectives in clinical research 2022-01, Vol.13 (1), p.54-57
Main Authors: Ranganathan, Priya, Pramesh, C, Aggarwal, Rakesh
Format: Article
Language:English
Subjects:
Clinical trials
Patient compliance
Quality of care
randomized controlled trials as topic
Research design
Research methodology
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Summary:Studies sometimes aim to show that a new intervention is not substantially worse than the existing standard of care while offering some benefits, for example, lower cost, decreased toxicity, or easier administration. Such studies are called non-inferiority (NI) trials. In this article, we look at some aspects of NI trials.
ISSN:2229-3485
2229-5488
DOI:10.4103/picr.picr_245_21