High sero-prevalence of hepatitis B virus and human immunodeficiency virus infections among pregnant women attending antenatal clinic at Temeke municipal health facilities, Dar es Salaam, Tanzania: a cross sectional study

Hepatitis B virus (HBV) and Human immunodeficiency virus (HIV) infection in pregnancy is associated with direct effect of pregnancy and potential viral transmission from mother to newborn. In Tanzania very little in known on prevalence of HBV infection and their associated factors among pregnant wom...

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Bibliographic Details
Published in:BMC pregnancy and childbirth 2017-04, Vol.17 (1), p.109-109, Article 109
Main Authors: Manyahi, Joel, Msigwa, Yohannes, Mhimbira, Francis, Majigo, Mtebe
Format: Article
Language:English
Subjects:
Adolescent
Adult
Ambulatory Care Facilities - statistics & numerical data
Antigens
Clinics
Coinfection - epidemiology
Coinfection - virology
Cross-Sectional Studies
Female
Growth rate
HBsAg
HBV
Health facilities
Hepatitis
Hepatitis B
Hepatitis B - epidemiology
Hepatitis B - virology
Hepatitis B virus
HIV
HIV Infections - epidemiology
HIV Infections - virology
Hospitals
Human immunodeficiency virus
Humans
Infections
Laboratories
Liver
Pregnancy
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - virology
Pregnant women
Prenatal Care - statistics & numerical data
Public health
Seroepidemiologic Studies
Syphilis
Tanzania
Tanzania - epidemiology
Vaccines
Womens health
Young Adult
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Summary:Hepatitis B virus (HBV) and Human immunodeficiency virus (HIV) infection in pregnancy is associated with direct effect of pregnancy and potential viral transmission from mother to newborn. In Tanzania very little in known on prevalence of HBV infection and their associated factors among pregnant women in lower health facilities. The main objective of the study was to determine the prevalence of HBsAg, HIV and HBV-HIV co-infection among pregnant women attending antenatal clinics in Dar es Salaam. This cross sectional study was conducted in three Temeke municipal health-care facilities between May 2014 and June 2014. A total of 249 pregnant women attending antenatal clinic (ANC) were consecutively enrolled in the study. A data collection tool was used to extract socio-demographic characteristics from ANC card. Commercial ARCHITECT® ci4100™ was used to assess HBsAg status and liver function (Alanine amino-transferase (ALAT). HIV status was determined by anti-HIV antibody test. Of 249 pregnant women enrolled the median age was 25 years (IQR 22-30) and most of them were married (72.4%). The overall prevalence of HBsAg and HIV were 8.03% (95% CI: 5.0-12.1%) and 17.2% (95% CI: 12.8-22.5%), respectively. HBV/HIV co-infection rate was 2.8% (95% CI; 1.3-5.4%). HBsAg positive rate was significantly high in women who were HIV positive (p 
ISSN:1471-2393
1471-2393
DOI:10.1186/s12884-017-1299-3