Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study

• Published in: BMC pregnancy and childbirth 2020-04, Vol.20 (1), p.222-10, Article 222
• Main Authors: Kim, Mi-La, Hong, Kirim, Kim, Sohyun, Lee, Min Jin, Shim, Sung Shin, Hur, Yoon-Mi, Shin, Joong Sik
• Format: Article
• Language: English
• Subjects: Abortion; Adult; Birth weight; Cesarean section; Childbirth & labor; Cohort analysis; Data analysis; Diabetes; Female; Fetuses; Fibroids; Gestational diabetes; Health risk assessment; Humans; Laparoscopy; Leiomyoma - epidemiology; Middle Aged; Obstetrics; Patients; Placenta; Pregnancy; Pregnancy Complications - epidemiology; Pregnancy Outcome; Pregnancy, Twin; Premature birth; Preterm delivery; Preterm labor; Previous myomectomy; Republic of Korea - epidemiology; Retrospective Studies; Twin pregnancy; Twins; Uterine fibroid; Uterine Myomectomy; Uterine Neoplasms - epidemiology
• ISSN: 1471-2393; 1471-2393
• DOI: 10.1186/s12884-020-02908-w

Twin pregnancies with uterine fibroid(s) (UFs) may not be at increased risk for obstetric complications compared to those without UFs. However, there was no reported comparison study with obstetric outcomes and complications of twin pregnancy after myomectomy. We aimed to compare the pregnancy outcomes in twin pregnancies with or without uterine fibroid(s), and also compared in patients with previous myomectomy history in Korean women. A cohort of twin pregnancies delivered in a single institution between January 2011 and March 2019 were retrospectively analyzed. UFs group was defined by the presence of UFs during pregnancy (≥1 fibroid, measuring ≥2 cm or multiple fibroids regardless of the size). Previous myomectomy group included patients with history of abdominal or laparoscopic or hysteroscopic myomectomy of ≥1 fibroid, measuring ≥2 cm or multiple fibroids whatever the size. Patients with monochorionic monoamniotic twins, myoma less than 2 cm in size, missed abortion or intrauterine fetal death (IUFD) of one fetus before 14 weeks, history of previous conization, and uterine anomalies were excluded. Pregnancy outcomes and obstetric complications were compared. A total 1388 patients were included in this study, 191 (13.8%) had UFs and 89 (6.4%) had a history of myomectomy. Maternal age was younger in non-UFs group and primiparity was more common in UFs group (p