New-Onset Atrial Fibrillation Is a Risk Factor of Ischemic Stroke in Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) induces atrial fibrillation (AF) and stroke, and COPD with AF increased ischemic stroke (IS) in a cross-sectional study. Therefore, healthcare providers must be concerned and well-informed about this particular situation. For this study, inpatient data we...

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Published in:Healthcare (Basel) 2022-02, Vol.10 (2), p.381
Main Authors: Liu, Chi-Chun, Chen, Yu-Hsuan, Chang, Yin-Han, Chien, Wu-Chien, Lin, Hui-Chen, Cheng, Chun-Gu, Cheng, Chun-An
Format: Article
Language:English
Subjects:
Age
Atherosclerosis
Cardiac arrhythmia
Cardiovascular disease
Chronic obstructive pulmonary disease
Codes
Comorbidity
Coronary vessels
Diabetes
Health insurance
Heart attacks
Heart failure
Hospitalization
Hospitals
Hypertension
ischemic stroke
Kidney diseases
Mortality
new-onset atrial fibrillation
Quality of life
Risk factors
Sepsis
Stroke
Vein & artery diseases
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Summary:Chronic obstructive pulmonary disease (COPD) induces atrial fibrillation (AF) and stroke, and COPD with AF increased ischemic stroke (IS) in a cross-sectional study. Therefore, healthcare providers must be concerned and well-informed about this particular situation. For this study, inpatient data were obtained from the Taiwan National Health Insurance Database in 2010. We identified patients who were hospitalized with COPD (International Classification of Disease, Ninth Revision, Clinical Modification [ICD-9-CM] is 491, 492, and 496). Patients who experienced AF (ICD-9-CM to 427.3) during the same admission or after COPD hospitalization were discharged and defined as new-onset AF. The outcome was IS (ICD-9-CM as 433-437). The factors related to IS after COPD were used for multivariate logistic regression. There were 4177/62,163 (6.72%) patients with incident IS. The risk of IS after COPD hospitalization was shown to have an adjusted odds ratio of 1.749 (95% CI: 1.584-1.93, < 0.001) for patients with new-onset AF. Other factors included advanced age, atherosclerosis factors, comorbidity severity, sepsis and lower-level hospital admission. In conclusion, COPD patients suffering from new-onset AF had an increased incidence of IS in the population observation study. New-onset AF was an omit risk factor for IS in COPD in the Chinese population.
ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare10020381