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Mechanical versus biological aortic valve implants in the elderly. A comparison of early and mid-term results
Our aim was to compare, in a non randomized study, the surgical outcome in elderly patients with mechanical (Group 1; n=83) and bioprosthetic valve implants (Group 2; n=136). During a three year period, 219 patients >75 years underwent Aortic Valve Replacement. The groups matched according to age...
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Published in: | Arquivos brasileiros de cardiologia 2001-11, Vol.77 (5), p.395-398 |
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description | Our aim was to compare, in a non randomized study, the surgical outcome in elderly patients with mechanical (Group 1; n=83) and bioprosthetic valve implants (Group 2; n=136).
During a three year period, 219 patients >75 years underwent Aortic Valve Replacement. The groups matched according to age, sex, comorbidity, valve pathology and concomitant Coronary Artery Bypass Surgery. Follow-up was a total of 469 patient-years (mean follow-up 2.1 years, maximum 4,4 years).
Operative mortality was zero and the overall early mortality was 2.3 % (within 30 days). Actuarial survival was 87.5 +/- 4.0% and 66.1 +/- 7.7% (NS) at 4 years in Group 1 and Group 2, respectively. Freedom from valve-related death was 88.9 +/- 3.8% in Group 1 and 69.9+/-7.9% (NS) in Group 2 at 4 years.
Aortic Valve Replacement in the elderly (>75 years) is a safe procedure even in cases where concomitant coronary artery revascularization is performed. Only a few anticoagulant-related complications were reported and this may indicate that selected groups of elderly patients with significant life expectancy may benefit from mechanical implants. |
doi_str_mv | 10.1590/S0066-782X2001001100001 |
format | article |
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During a three year period, 219 patients >75 years underwent Aortic Valve Replacement. The groups matched according to age, sex, comorbidity, valve pathology and concomitant Coronary Artery Bypass Surgery. Follow-up was a total of 469 patient-years (mean follow-up 2.1 years, maximum 4,4 years).
Operative mortality was zero and the overall early mortality was 2.3 % (within 30 days). Actuarial survival was 87.5 +/- 4.0% and 66.1 +/- 7.7% (NS) at 4 years in Group 1 and Group 2, respectively. Freedom from valve-related death was 88.9 +/- 3.8% in Group 1 and 69.9+/-7.9% (NS) in Group 2 at 4 years.
Aortic Valve Replacement in the elderly (>75 years) is a safe procedure even in cases where concomitant coronary artery revascularization is performed. Only a few anticoagulant-related complications were reported and this may indicate that selected groups of elderly patients with significant life expectancy may benefit from mechanical implants.</description><identifier>ISSN: 0066-782X</identifier><identifier>ISSN: 1678-4170</identifier><identifier>EISSN: 0066-782X</identifier><identifier>EISSN: 1678-4170</identifier><identifier>DOI: 10.1590/S0066-782X2001001100001</identifier><identifier>PMID: 11733813</identifier><language>eng</language><publisher>Brazil: Sociedade Brasileira de Cardiologia - SBC</publisher><subject>Aged ; Aged, 80 and over ; aortic valve ; Aortic Valve - surgery ; Bioprosthesis ; CARDIAC & CARDIOVASCULAR SYSTEMS ; cardiac surgery ; elderly ; Female ; Follow-Up Studies ; heart valve prosthesis ; Heart Valve Prosthesis Implantation - methods ; Heart Valve Prosthesis Implantation - mortality ; Humans ; Male ; Retrospective Studies ; Survival Rate ; Treatment Outcome</subject><ispartof>Arquivos brasileiros de cardiologia, 2001-11, Vol.77 (5), p.395-398</ispartof><rights>This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3781-9a34692ff66922e88e6eb4ffae408f5481b2e48d23a521cb6bb1badb298de5dc3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,24131,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11733813$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thulin, L I</creatorcontrib><creatorcontrib>Sjögren, J L</creatorcontrib><title>Mechanical versus biological aortic valve implants in the elderly. A comparison of early and mid-term results</title><title>Arquivos brasileiros de cardiologia</title><addtitle>Arq Bras Cardiol</addtitle><description>Our aim was to compare, in a non randomized study, the surgical outcome in elderly patients with mechanical (Group 1; n=83) and bioprosthetic valve implants (Group 2; n=136).
During a three year period, 219 patients >75 years underwent Aortic Valve Replacement. The groups matched according to age, sex, comorbidity, valve pathology and concomitant Coronary Artery Bypass Surgery. Follow-up was a total of 469 patient-years (mean follow-up 2.1 years, maximum 4,4 years).
Operative mortality was zero and the overall early mortality was 2.3 % (within 30 days). Actuarial survival was 87.5 +/- 4.0% and 66.1 +/- 7.7% (NS) at 4 years in Group 1 and Group 2, respectively. Freedom from valve-related death was 88.9 +/- 3.8% in Group 1 and 69.9+/-7.9% (NS) in Group 2 at 4 years.
Aortic Valve Replacement in the elderly (>75 years) is a safe procedure even in cases where concomitant coronary artery revascularization is performed. Only a few anticoagulant-related complications were reported and this may indicate that selected groups of elderly patients with significant life expectancy may benefit from mechanical implants.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>aortic valve</subject><subject>Aortic Valve - surgery</subject><subject>Bioprosthesis</subject><subject>CARDIAC & CARDIOVASCULAR SYSTEMS</subject><subject>cardiac surgery</subject><subject>elderly</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>heart valve prosthesis</subject><subject>Heart Valve Prosthesis Implantation - methods</subject><subject>Heart Valve Prosthesis Implantation - mortality</subject><subject>Humans</subject><subject>Male</subject><subject>Retrospective Studies</subject><subject>Survival Rate</subject><subject>Treatment Outcome</subject><issn>0066-782X</issn><issn>1678-4170</issn><issn>0066-782X</issn><issn>1678-4170</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNp9UU1v1DAQjRCIlsJfAJ-4ZfFHHDvHqqJQqYgDIHGzxvak9cqJFztZqf8ed3dVkJCQ7Bnred6bsV_TvGN0w-RAP3yjtO9bpflPTimrq-4anzXnTxfP_zqfNa9K2VLKuRLyZXPGmBJCM3HeTF_Q3cMcHESyx1zWQmxIMd0dEEh5CY7sIe6RhGkXYV4KCTNZ7pFg9Jjjw4ZcEpemHeRQ0kzSSBAqTGD2ZAq-XTBPJGNZ41JeNy9GiAXfnPJF8-P64_erz-3t1083V5e3rRNKs3YA0fUDH8e-Ro5aY4-2G0fAjupRdppZjp32XIDkzNneWmbBWz5oj9I7cdHcHHV9gq3Z5TBBfjAJgjkAKd8ZeHxZRAPS9VxqLin3HVUwdAPVDjWVbFSesqq1OWoVFzAms01rnuvw5uCB-ceDSnh_JOxy-rViWcwUisNYPw_TWozigkulVC1Ux0KXUykZx6dJGTWPNv-nxdtTi9VO6P_wTr6K30gKoOQ</recordid><startdate>20011101</startdate><enddate>20011101</enddate><creator>Thulin, L I</creator><creator>Sjögren, J L</creator><general>Sociedade Brasileira de Cardiologia - SBC</general><general>Sociedade Brasileira de Cardiologia (SBC)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>GPN</scope><scope>DOA</scope></search><sort><creationdate>20011101</creationdate><title>Mechanical versus biological aortic valve implants in the elderly. A comparison of early and mid-term results</title><author>Thulin, L I ; Sjögren, J L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3781-9a34692ff66922e88e6eb4ffae408f5481b2e48d23a521cb6bb1badb298de5dc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>aortic valve</topic><topic>Aortic Valve - surgery</topic><topic>Bioprosthesis</topic><topic>CARDIAC & CARDIOVASCULAR SYSTEMS</topic><topic>cardiac surgery</topic><topic>elderly</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>heart valve prosthesis</topic><topic>Heart Valve Prosthesis Implantation - methods</topic><topic>Heart Valve Prosthesis Implantation - mortality</topic><topic>Humans</topic><topic>Male</topic><topic>Retrospective Studies</topic><topic>Survival Rate</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thulin, L I</creatorcontrib><creatorcontrib>Sjögren, J L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SciELO</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Arquivos brasileiros de cardiologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thulin, L I</au><au>Sjögren, J L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mechanical versus biological aortic valve implants in the elderly. A comparison of early and mid-term results</atitle><jtitle>Arquivos brasileiros de cardiologia</jtitle><addtitle>Arq Bras Cardiol</addtitle><date>2001-11-01</date><risdate>2001</risdate><volume>77</volume><issue>5</issue><spage>395</spage><epage>398</epage><pages>395-398</pages><issn>0066-782X</issn><issn>1678-4170</issn><eissn>0066-782X</eissn><eissn>1678-4170</eissn><abstract>Our aim was to compare, in a non randomized study, the surgical outcome in elderly patients with mechanical (Group 1; n=83) and bioprosthetic valve implants (Group 2; n=136).
During a three year period, 219 patients >75 years underwent Aortic Valve Replacement. The groups matched according to age, sex, comorbidity, valve pathology and concomitant Coronary Artery Bypass Surgery. Follow-up was a total of 469 patient-years (mean follow-up 2.1 years, maximum 4,4 years).
Operative mortality was zero and the overall early mortality was 2.3 % (within 30 days). Actuarial survival was 87.5 +/- 4.0% and 66.1 +/- 7.7% (NS) at 4 years in Group 1 and Group 2, respectively. Freedom from valve-related death was 88.9 +/- 3.8% in Group 1 and 69.9+/-7.9% (NS) in Group 2 at 4 years.
Aortic Valve Replacement in the elderly (>75 years) is a safe procedure even in cases where concomitant coronary artery revascularization is performed. Only a few anticoagulant-related complications were reported and this may indicate that selected groups of elderly patients with significant life expectancy may benefit from mechanical implants.</abstract><cop>Brazil</cop><pub>Sociedade Brasileira de Cardiologia - SBC</pub><pmid>11733813</pmid><doi>10.1590/S0066-782X2001001100001</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Aged, 80 and over aortic valve Aortic Valve - surgery Bioprosthesis CARDIAC & CARDIOVASCULAR SYSTEMS cardiac surgery elderly Female Follow-Up Studies heart valve prosthesis Heart Valve Prosthesis Implantation - methods Heart Valve Prosthesis Implantation - mortality Humans Male Retrospective Studies Survival Rate Treatment Outcome |
title | Mechanical versus biological aortic valve implants in the elderly. A comparison of early and mid-term results |
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