Optimal margins for early stage peripheral lung adenocarcinoma resection

A pathologically confirmed negative margin is required when performing sublobar resection in patients with early stage peripheral lung adenocarcinoma. However, the optimal margin distance to ensure complete tumor resection while preserving healthy lung tissue remains unknown. We aimed to establish a...

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Bibliographic Details
Published in:BMC cancer 2021-05, Vol.21 (1), p.533-533, Article 533
Main Authors: Yin, Pan, Yue, Bingqing, Zhang, Ji, Liu, Dong, Bai, Dongyu, Zhao, Guang, Huang, Chutong, Geng, Guojun, Jiang, Jie, Su, Yongxiang, Yu, Xiuyi, Chen, Jingyu
Format: Article
Language:English
Subjects:
Adenocarcinoma
Care and treatment
Hematoxylin and eosin staining
Hyperplasia
Lung cancer
Lungs
Margin distance
Medical screening
Pathological outcomes
Patients
Peripheral lung adenocarcinoma
Prognosis
Safety
Sublobar resection
Surgery
Tumors
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Summary:A pathologically confirmed negative margin is required when performing sublobar resection in patients with early stage peripheral lung adenocarcinoma. However, the optimal margin distance to ensure complete tumor resection while preserving healthy lung tissue remains unknown. We aimed to establish a reliable distance range for negative margins. A total of 52 intraoperative para-cancer tissue specimens from patients with peripheral lung adenocarcinoma with pathological tumors ≤2 cm in size were examined. Depending on the distance from the tumor edge (D), the para-cancer tissues were divided into the following five groups: D 
ISSN:1471-2407
1471-2407
DOI:10.1186/s12885-021-08251-3