A Comparative Review of Key Isothiocyanates and Their Health Benefits

Isothiocyanates are biologically active products resulting from the hydrolysis of glucosinolates predominantly present in cruciferous vegetables belonging to the family. Numerous studies have demonstrated the diverse bioactivities of various isothiocyanates, encompassing anticarcinogenic, anti-infla...

Full description

Saved in:
Bibliographic Details
Published in:Nutrients 2024-03, Vol.16 (6), p.757
Main Authors: Olayanju, Julia B, Bozic, Dragica, Naidoo, Uma, Sadik, Omowunmi A
Format: Article
Language:English
Subjects:
Acids
Anti-Inflammatory Agents
anticarcinogenic
Anticarcinogenic Agents - pharmacology
Antidiabetics
Antioxidants - pharmacology
antitumor
Bioavailability
Biological activity
Brassicaceae - chemistry
Cancer
Carcinogens
chemoprevention
Comparative analysis
Cytochrome
Cytokines
Disease
Enzymes
Glucosinolates - pharmacology
Health insurance
Hydrolysis
Investigations
isothiocyanate
Isothiocyanates - pharmacology
Metabolism
Metabolites
Oxidative stress
Proteins
Review
Tumor necrosis factor-TNF
Urine
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Isothiocyanates are biologically active products resulting from the hydrolysis of glucosinolates predominantly present in cruciferous vegetables belonging to the family. Numerous studies have demonstrated the diverse bioactivities of various isothiocyanates, encompassing anticarcinogenic, anti-inflammatory, and antioxidative properties. Nature harbors distinct isothiocyanate precursors, glucosinolates such as glucoraphanin and gluconastrin, each characterized by unique structures, physical properties, and pharmacological potentials. This comprehensive review aims to consolidate the current understanding of isothiocyanates, mainly 4-[(α-L-rhamnosyloxy) benzyl] isothiocyanate), comparing this compound with other well-studied isothiocyanates such as sulforaphane and phenyl ethyl isothiocyanates. The focus is directed toward elucidating differences and similarities in the efficacy of these compounds as agents with anticancer, anti-inflammatory, and antioxidative properties.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu16060757