Recurrence of acute myeloid leukemia in cryptorchid testis: case report

A 23-year-old male with a history of bone marrow transplant for acute myeloid leukemia. He presented a large mass in the right inguinal region 5 years ago. Upon physical examination, right-sided cryptorchidism was observed. The tumor markers alpha-fetoprotein and beta-HCG were within normalcy range...

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Bibliographic Details
Published in:Einstein (São Paulo, Brazil) Brazil), 2014-01, Vol.12 (1), p.109-111
Main Authors: Góes, Luccas Santos Patto de, Lopes, Roberto Iglesias, Campos, Octavio Henrique Arcos, Oliveira, Luiz Carlos Neves de, Sant'Anna, Alexandre Crippa, Dall'Oglio, Marcos Francisco, Srougi, Miguel
Format: Article
Language:English
Subjects:
Biopsy
Bone Marrow Transplantation
Case Report
Criptorquidismo
Cryptorchidism - pathology
Cryptorchidism - surgery
Humans
Leucemia mieloide aguda
Leukemia, Myeloid, Acute - pathology
Leukemia, Myeloid, Acute - surgery
Male
MEDICINE, GENERAL & INTERNAL
Neoplasias testiculares
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - surgery
Orchiectomy - methods
Orquiectomia
Quimioterapia adjuvante
Recidiva
Relatos de casos
Testicular Neoplasms - pathology
Testicular Neoplasms - surgery
Tomography, X-Ray Computed
Treatment Outcome
Young Adult
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Summary:A 23-year-old male with a history of bone marrow transplant for acute myeloid leukemia. He presented a large mass in the right inguinal region 5 years ago. Upon physical examination, right-sided cryptorchidism was observed. The tumor markers alpha-fetoprotein and beta-HCG were within normalcy range and lactate dehydrogenase was raised. Computed tomography of the abdomen and pelvis revealed right testicular mass in contiguity with the inguinal canal to the ipsilateral retroperitoneum, associated with right hydronephrosis. Due to the risk of germ-cell tumor in undescended testicle, the patient underwent radical right orchiectomy. The pathological examination showed recurrence of acute myeloid leukemia in the testis. He was referred to oncology for adjuvant therapy. Our literature review found no similar cases described.
ISSN:1679-4508
2317-6385
2317-6385
1679-4508
DOI:10.1590/S1679-45082014RC2689