A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab

A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI p...

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Bibliographic Details
Published in:Urology case reports 2015-03, Vol.3 (2), p.9-11
Main Authors: Kanamaru, Tomohiro, Iguchi, Taro, Yukimatsu, Nao, Shimizu, Yasuomi, Kohyama, Yuki, Tachibana, Hirokazu, Kato, Minoru, Yamasaki, Takeshi, Tamada, Satoshi, Nakatani, Tatsuya
Format: Article
Language:English
Subjects:
Bevacizumab
Chemotherapy
FOLFIRI
Oncology
Urachal carcinoma
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Summary:A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI plus bevacizumab chemotherapy as salvage chemotherapy. Stability was achieved after eight cycles of FOLFIRI plus bevacizumab therapy. We conducted a biopsy of the metastatic tumor, and the pathology of the biopsy tissue was partially necrotic. To our knowledge, this case represents the first report of a metastatic urachal carcinoma treated with FOLFIRI plus bevacizumab.
ISSN:2214-4420
2214-4420
DOI:10.1016/j.eucr.2014.11.004