Use of Ovostim-CT in the prevention of hepatosis and retention of placenta in cows after calving

• Published in: E3S web of conferences 2021, Vol.282, p.3014
• Main Author: Burkov, P.V.
• Format: Article
• Language: English
• Subjects: Albumins; Blood; Complications; Cow's milk; Cytotoxicity; Dairy cattle; Damage prevention; Dosage; Liver; Milk; Muscles; Placenta; Postpartum; Prevention; Proteins; Retention; Retirement; Spleen
• ISSN: 2267-1242; 2555-0403; 2267-1242
• DOI: 10.1051/e3sconf/202128203014

High milk productivity of cows after calving is the cause of liver damage in the form of hepatosis and premature retirement of animals. In such cases, a pathological examination simultaneously reveals violations in the form of protein and fatty degenerations with the subsequent destruction of cells, as well as disturbed circulation in the liver. Also, hepatoses can cause such postpartum complications in cows as retention of placenta. For the prevention of hepatosis, the drug “Ovostim-ct” is proposed, which contains cytotoxic sera against the tissues of the liver, ovary, spleen and muscle. In order to prevent liver damage and postpartum retention of placenta, the drug is used 1-1.5 months before calving at a dose of 1 ml per 100 kg of live weight subcutaneously or intramuscularly. The use of the hepatoprotector allowed to reduce the number of cases of hepatosis and retention of placenta in cows after calving. Also, “Ovostim-ct” had a favorable effect on the biochemical parameters of the blood serum of cows: there was an increase in the concentration of total protein by 6.7%, albumin - by 15.6% and glucose - by 45.8% in the blood.