Bilateral xanthogranulomatous inflammation of nasal and nasopharynx mass: a case report

Background Xanthogranulomatous inflammation is an uncommon condition in adult nasal cavity and nasopharynx. Case presentation We report a male patient who developed xanthogranulomatous inflammation in the bilateral nose and nasopharynx. The patient was not responsive to oral steroid. Multiple biopsi...

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Bibliographic Details
Published in:The Egyptian journal of otolaryngology 2022-12, Vol.38 (1), p.1-5, Article 12
Main Authors: Boon, Wei Jie, Vong, Khim Soon, Tang, Ing Ping
Format: Article
Language:English
Subjects:
Case Report
Histochemistry
Inflammation
Medicine
Medicine & Public Health
Nasal cavity mass
Nasopharynx mass
Surgery
Xanthogranulomatous inflammation
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Summary:Background Xanthogranulomatous inflammation is an uncommon condition in adult nasal cavity and nasopharynx. Case presentation We report a male patient who developed xanthogranulomatous inflammation in the bilateral nose and nasopharynx. The patient was not responsive to oral steroid. Multiple biopsies were taken to confirm the definitive diagnosis, and endoscopic debulking of mass was performed to provide symptomatic relief. Patient was free from nasal symptoms, and residual nasal and nasopharyngeal masses showed no increment in size and number during follow-up. Conclusion Xanthogranulomatous inflammation in the nasal cavity and nasopharynx can be easily confused with other nasal masses. A histopathology examination is crucial to establish the diagnosis. A repeated biopsy is needed if previous biopsy result is inconclusive. Surgical excision is recommended for symptomatic relief. The effectiveness of medical treatment is still unclear. A long-term follow-up is mandatory.
ISSN:1012-5574
2090-8539
DOI:10.1186/s43163-022-00201-5