Penetrating cardiac injury after percutaneous breast core-needle biopsy, unusual life-threatening complication: a case report

• Published in: Journal of medical case reports 2024-09, Vol.18 (1), p.435-5, Article 435
• Main Authors: Kanlerd, Amonpon, Sujarittanakarn, Sasithorn, Lohitvisate, Wanrudee
• Format: Article
• Language: English
• Subjects: Biopsy, Large-Core Needle - adverse effects; Breast - pathology; Breast Neoplasms - pathology; Cardiac patients; Cardiac tamponade; Cardiac Tamponade - etiology; Case report; Complication; Complications and side effects; Coronary artery bypass; Echocardiography; Fainting; Female; Heart Injuries - etiology; Heart Ventricles - injuries; Heart Ventricles - pathology; Humans; Infection; Middle Aged; Penetrating cardiac injury; Percutaneous breast biopsy; Pericardial Window Techniques - adverse effects; Risk factors
• ISSN: 1752-1947; 1752-1947
• DOI: 10.1186/s13256-024-04731-9

Complications after percutaneous breast biopsy are infrequent but may include hematoma, pseudoaneurysm formation, persistent pain, infection, delayed wound healing, vasovagal reaction, hemothorax, pneumothorax, and neoplastic seeding. The risk factors include tumor factors (size, location, vascularity), procedure-related factors (needle diameter, number of biopsies), and interventionist experience. There has been no previous report of a fatal complication resulting from percutaneous breast biopsy. We report a 54-year-old Asian woman with a 3 cm BI-RADS 4B left breast mass in the lower-inner quadrant who was biopsied by a 16 G needle under ultrasound guidance at a province hospital. She experienced dizziness and near-syncope afterward. The initial evaluation showed evidence of cardiac tamponade with hemodynamic instability. She underwent urgent subxiphoid pericardial window and was transferred to our facility. We brought her directly to the operating room to perform an explorative median sternotomy and found a 0.2 cm hole in the right ventricle. The injured site was successfully repaired without cardiopulmonary bypass. Postoperative echocardiography demonstrated mild right ventricular dysfunction without evidence of septal or valvular injury. She survived with no significant complications. This case might be the first report of a life-threatening complication related to percutaneous breast core-needle biopsy. The rapid pericardial release is key to the survival of cardiac tamponade. The patient subsequently required cardiac repair and monitoring to avoid long-term complications. In this report, we suggested a safe biopsy method, complications recognition, and appropriate management of penetrating cardiac injury. Penetrating cardiac injury resulting from percutaneous breast biopsy is extremely rare but can occur. A biopsy must be done cautiously, and worst-case management should promptly be considered.