Efficient Synthesis of Novel Phostone and Phostam Derivatives via Regioselective Intramolecular Heck Cyclizations of (2-Iodobenzyl)buta-1,3-dienylphosphonates, (2-Iodophenyl)buta-1,3-dienylphosphonates, and N‑(2-Iodophenyl)‑P‑buta-1,3-dienylphosphonamidates

Here, we report the intramolecular Heck cross-coupling of 1,3-dienylphosphonates, affording unique and regioselective access to unprecedented benzofused phostone and phostam derivatives. The reactions proceeded under operationally simple and mild conditions with a wide substrate scope.

Saved in:
Bibliographic Details
Published in:ACS omega 2024-11, Vol.9 (44), p.44542-44548
Main Authors: Sanaa, Hamdi, Touil, Soufiane, Durandetti, Muriel, Samarat, Ali
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Here, we report the intramolecular Heck cross-coupling of 1,3-dienylphosphonates, affording unique and regioselective access to unprecedented benzofused phostone and phostam derivatives. The reactions proceeded under operationally simple and mild conditions with a wide substrate scope.
ISSN:2470-1343
2470-1343
DOI:10.1021/acsomega.4c06616