A prospective survey on trephine biopsy of bone and bone marrow: an experience with 274 Indian patients' biopsies

Trephine bone marrow biopsy is an effective technique for diagnosing hematological malignancies in patients of different ages. During trephine biopsy, bone marrow cores are obtained for detailed morphological evaluation to look for any abnormality and arrive at a diagnosis. The primary goal of this...

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Bibliographic Details
Published in:European journal of medical research 2023-06, Vol.28 (1), p.193-193, Article 193
Main Authors: Nadda, Rahul, Repaka, Ramjee, Mallik, Nabhajit, Sahani, Ashish Kumar
Format: Article
Language:English
Subjects:
Adults
Anesthesia
Anxiety
Biopsy
Bone and Bones
Bone marrow
Bone Marrow - pathology
Clinical analysis
College graduates
Gender
Hematologic Neoplasms
Hematology
Humans
Pain
Patients
Pediatrics
Prospective Studies
Questionnaires
Search engines
Survey
Surveys
Trephine biopsy
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Summary:Trephine bone marrow biopsy is an effective technique for diagnosing hematological malignancies in patients of different ages. During trephine biopsy, bone marrow cores are obtained for detailed morphological evaluation to look for any abnormality and arrive at a diagnosis. The primary goal of this work is to perform a survey on Indian patients of various ages for the trephine bone marrow biopsy process. In the present study, data related to 274 trephine biopsy samples from 300 patients were acquired at the Post Graduate Institute of Medical Education and Research (PGIMER) in Chandigarh, India. Pain was found to be the sole major procedure-related complication, and patients reported no/less pain in 41 BMB (14.96%) patients, moderate pain in 82 (29.92%) cases, and unbearable pain in 151 (55.1%) BMB cases. In addition, the patients were evaluated by the authors and hematologist as non-anxious for the procedure in 34 (12.4%), anxious in 92 (33.57%), and very/highly anxious in 148 (56%) cases. The bone texture of the patients significantly affected the needle bending, number of repetitions required, and size of the bone marrow sample. This demonstrates the need for improvement in the biopsy procedure. To this end, a survey was conducted to assess the numerous difficulties and diagnostic outcomes throughout the trephine biopsy process.
ISSN:2047-783X
0949-2321
2047-783X
DOI:10.1186/s40001-023-01167-7