Association of Three Novel Inflammatory Markers: Lymphocyte to HDL‐C Ratio, High‐Sensitivity C‐Reactive Protein to HDL‐C Ratio and High‐Sensitivity C‐Reactive Protein to Lymphocyte Ratio With Metabolic Syndrome

ABSTRACT Objective We aimed to compare the association of three novel inflammatory indicators with metabolic syndrome (MetS) among Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort participants. Methods According to the International Diabetes Federation (IDF) criteria, the cohort par...

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Published in:Endocrinology, diabetes & metabolism diabetes & metabolism, 2024-05, Vol.7 (3), p.e00479-n/a
Main Authors: Kolahi Ahari, Rana, Akbari, Nazanin, Babaeepoor, Negin, Fallahi, Zahra, Saffar Soflaei, Sara, Ferns, Gordon, Ebrahimi, Mahmoud, Moohebati, Mohsen, Esmaily, Habibollah, Ghayour‐Mobarhan, Majid
Format: Article
Language:English
Subjects:
Atherosclerosis
Blood pressure
Body mass index
C-Reactive Protein - metabolism
Cholesterol
Cholesterol, HDL
Diabetes
Diabetes Mellitus
Exercise
Female
Hematology
High density lipoprotein
high‐sensitivity C‐reactive protein to HDL‐C ratio
high‐sensitivity C‐reactive protein to lymphocyte ratio
Humans
Hypertension
Inflammation
Lipids
Lipoproteins
lymphocyte to HDL‐C ratio
Lymphocytes
Lymphocytes - metabolism
Male
Metabolic syndrome
Metabolic Syndrome - diagnosis
Metabolic Syndrome - etiology
Metabolic Syndrome - metabolism
Obesity
Proteins
Regression analysis
Statistical analysis
Uric acid
Variables
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Summary:ABSTRACT Objective We aimed to compare the association of three novel inflammatory indicators with metabolic syndrome (MetS) among Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort participants. Methods According to the International Diabetes Federation (IDF) criteria, the cohort participants were divided into the MetS(+) and MetS(−) groups. The lymphocyte to high‐density lipoprotein cholesterol (HDL‐C) ratio (LHR), high‐sensitivity C‐reactive protein (hs‐CRP) to HDL‐C ratio (HCHR) and hs‐CRP to lymphocyte ratio (HCLR) were calculated and were compared between the groups. Binary logistic regression (LR) analysis was performed to find the association of the indices with the presence of MetS among men and women. Receiver‐operating characteristic (ROC) curve analysis was used to establish cut‐off values in predicting MetS for men and women. p‐Values
ISSN:2398-9238
2398-9238
DOI:10.1002/edm2.479