Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders

The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5–15 yrs) with a diagnosed MD or NMD...

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Published in:International Journal of Pediatrics 2010-01, Vol.2010 (2010), p.60-65
Main Authors: Visser, Gepke, Prinsen, Berthil H., van Hasselt, Peter M., Helders, Paul J., Ernsting, Cornelia G., Hulzebos, Erik H., Takken, Tim, Groen, Wim G.
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Clinical Study
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cited_by cdi_FETCH-LOGICAL-a4479-b55f95c629998aca27c56ddfc87a76809dbcf7bed7a82f2e5a38ee4365d067f13
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container_end_page 65
container_issue 2010
container_start_page 60
container_title International Journal of Pediatrics
container_volume 2010
creator Visser, Gepke
Prinsen, Berthil H.
van Hasselt, Peter M.
Helders, Paul J.
Ernsting, Cornelia G.
Hulzebos, Erik H.
Takken, Tim
Groen, Wim G.
description The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5–15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.
doi_str_mv 10.1155/2010/254829
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title Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders
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