Acute exacerbation of unclassifiable idiopathic interstitial pneumonia: comparison with idiopathic pulmonary fibrosis

Background: Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is well known as a life-threatening condition during its clinical course. However, the clinical features and prognosis in AE of unclassifiable idiopathic interstitial pneumonia (AE-UCIIP) remain to be elucidated. The aim of thi...

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Published in:Therapeutic advances in respiratory disease 2020, Vol.14, p.1753466620935774-1753466620935774
Main Authors: Enomoto, Noriyuki, Naoi, Hyogo, Aono, Yuya, Katsumata, Mineo, Horiike, Yasuoki, Yasui, Hideki, Karayama, Masato, Hozumi, Hironao, Suzuki, Yuzo, Furuhashi, Kazuki, Fujisawa, Tomoyuki, Inui, Naoki, Nakamura, Yutaro, Suda, Takafumi
Format: Article
Language:English
Subjects:
Medical prognosis
Original Research
Pneumonia
Pulmonary fibrosis
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Summary:Background: Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is well known as a life-threatening condition during its clinical course. However, the clinical features and prognosis in AE of unclassifiable idiopathic interstitial pneumonia (AE-UCIIP) remain to be elucidated. The aim of this study was to clarify the clinical features and prognosis of AE-UCIIP compared with those of AE-IPF. Methods: In 187 patients with UCIIP or IPF, 64 patients with AE-UCIIP or AE-IPF, who were diagnosed and treated at our hospital, were retrospectively evaluated. Results: A total of 24 patients with AE-UCIIP were significantly older (p = 0.011), included more women (p 
ISSN:1753-4666
1753-4658
1753-4666
DOI:10.1177/1753466620935774