A Clinical Study on Musculoskeletal Changes Seen in Type 2 Diabetes Mellitus: A Single-Center Study

• Published in: APIK Journal of Internal Medicine 2024-01, Vol.12 (1), p.24-28
• Main Authors: Jayashankar, C. A., Vasu, Sharanya Anasosalu, Mathew, Harsha Anie, Pinnelli, Venkata Bharat Kumar, Shalini, A. S., Spandana, S. P.
• Format: Article
• Language: English
• Subjects: diabetes mellitus; microvascular complications; musculoskeletal manifestation
• ISSN: 2666-1802; 2666-1802
• DOI: 10.4103/ajim.ajim_90_22

Background: Type 2 Diabetes mellitus (T2DM) may affect the musculoskeletal (MSK) system in a variety of ways. The impacts can be debilitating enough to impair functional ability and quality of life. MSK complications are the most common endocrine arthropathies which are often under-recognized and poorly treated. This study was done to evaluate the prevalence of MSK complications and its correlation with microvascular complications of T2DM given the paucity of similar studies in India particularly South India. Materials and Methods: A cross-sectional study was conducted on 130 diabetic patients at a tertiary care hospital in Bengaluru. The patient's demographic details, clinical profile including history, general physical examination, systemic examination, and relevant investigations were done to record microvascular complications. A thorough MSK system examination along with imaging of bones and joints was also performed. Results: Out of 130 diabetic patients, 21 patients (16.2%) had MSK complications of which 47.6% (n = 10) of them had carpal tunnel syndrome and 42.8% (n = 9) had frozen shoulder and 9.5% (n = 2) had diabetic amyotrophy. It was also noted that patients who were on oral hypoglycemic agents alone were more likely to develop MSK complications (57.14%) than patients solely on insulin (14.2%). Poor glycemic control, existing microvascular complications, and low high-density lipoprotein were found to be associated with increased risk of MSK complications. Conclusion: The prevalence of MSK complications in T2DM patients is quite significant and is also associated with microvascular complications. Improved glycemic control in T2DM was found to reduce the burden of such complications. Early identification of MSK complications can improve the quality of life in diabetic patients and hence demands proper screening and follow-up.