IgY Antibodies as Biotherapeutics in Biomedicine

Since the discovery of antibodies by Emil Von Behring and Shibasaburo Kitasato during the 19th century, their potential for use as biotechnological reagents has been exploited in different fields, such as basic and applied research, diagnosis, and the treatment of multiple diseases. Antibodies are r...

Full description

Saved in:
Bibliographic Details
Published in:Antibodies (Basel) 2022-09, Vol.11 (4), p.62
Main Authors: León-Núñez, Diana, Vizcaíno-López, María Fernanda, Escorcia, Magdalena, Correa, Dolores, Pérez-Hernández, Elizabeth, Gómez-Chávez, Fernando
Format: Article
Language:English
Subjects:
Adaptive systems
Animals
Antibodies
Bacteria
Biotechnology
biotherapeutics
Birds
Dengue fever
Diagnosis
Ebola virus
Experimentation
Health aspects
Identification and classification
IgY
Immune system
Immunoglobulins
Influenza
Lymphocytes
Medical diagnosis
Medical research
Middle East respiratory syndrome
Pathogens
Reagents
Reptiles & amphibians
Respiratory diseases
Review
Rotavirus
Severe acute respiratory syndrome coronavirus 2
treatment
Yolk
Zika virus
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Since the discovery of antibodies by Emil Von Behring and Shibasaburo Kitasato during the 19th century, their potential for use as biotechnological reagents has been exploited in different fields, such as basic and applied research, diagnosis, and the treatment of multiple diseases. Antibodies are relatively easy to obtain from any species with an adaptive immune system, but birds are animals characterized by relatively easy care and maintenance. In addition, the antibodies they produce can be purified from the egg yolk, allowing a system for obtaining them without performing invasive practices, which favors the three “rs” of animal care in experimentation, i.e., replacing, reducing, and refining. In this work, we carry out a brief descriptive review of the most outstanding characteristics of so-called “IgY technology” and the use of IgY antibodies from birds for basic experimentation, diagnosis, and treatment of human beings and animals.
ISSN:2073-4468
2073-4468
DOI:10.3390/antib11040062