ID1 and IGFBP3: roles in cellular senescence, cardiac development, angiogenesis and cancer diagnosis

ID1 and IGFBP3 in prostate cancer Research indicates that normal prostate epithelial cells display low or virtually non-existent ID1 expression levels, contrasting with the heightened levels observed in prostate cancer. [...]the integration of ID1 into normal prostate epithelial cells might present...

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Bibliographic Details
Published in:Journal of translational medicine 2023-11, Vol.21 (1), p.1-797, Article 797
Main Author: Shen, Cheng
Format: Article
Language:English
Subjects:
Angiogenesis
Epithelial cells
Id1 protein
Insulin-like growth factor-binding protein 3
Insulin-like growth factors
Letter to the Editor
Medical research
Prostate cancer
Proteins
Senescence
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Summary:ID1 and IGFBP3 in prostate cancer Research indicates that normal prostate epithelial cells display low or virtually non-existent ID1 expression levels, contrasting with the heightened levels observed in prostate cancer. [...]the integration of ID1 into normal prostate epithelial cells might present a method for examining the early stages involved in the onset of prostate cancer. [...]ID1 and IGFBP3 each have their own unique biological properties, and there are currently few research results on the relationship between them. [...]exploring the mechanisms that underlie this specificity would be a compelling area for future research.
ISSN:1479-5876
1479-5876
DOI:10.1186/s12967-023-04701-7