Label-free detection of leukemic myeloblasts in hyaluronic acid

Chronic myeloid leukemia is generally required bone marrow biopsy for diagnosis. Although examining peripheral blood is less invasive, it has not been fully validated as a routine diagnostic test due to suboptimal sensitivity. To overcome this limitation, a number of methodologies based on microflui...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biological engineering 2022-11, Vol.16 (1), p.1-29, Article 29
Main Authors: Park, Suhyun, Kim, Hyueyun, Woo, Minna, Kim, Minsuk
Format: Article
Language:English
Subjects:
Analysis
Biopsy
Blood
Blood circulation
Bone marrow
Chronic myeloid leukemia
Digital cameras
Drug efficacy
Fluctuations
Hyaluronic acid
Invasiveness
Leukemia
Methodology
Microfluidic system
Microfluidics
Microscopy
Motion microscopy
Myeloid leukemia
Newtonian fluids
Non Newtonian fluids
Peripheral blood
Proteins
Sensitivity analysis
Shear stress
Tumor cells
Variance analysis
Vibration
Viscosity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c574t-ceb70dfa2a81f42eb0afba9b0623a8fb374feac99d1d16484a2ab428582f0a573
cites cdi_FETCH-LOGICAL-c574t-ceb70dfa2a81f42eb0afba9b0623a8fb374feac99d1d16484a2ab428582f0a573
container_end_page 29
container_issue 1
container_start_page 1
container_title Journal of biological engineering
container_volume 16
creator Park, Suhyun
Kim, Hyueyun
Woo, Minna
Kim, Minsuk
description Chronic myeloid leukemia is generally required bone marrow biopsy for diagnosis. Although examining peripheral blood is less invasive, it has not been fully validated as a routine diagnostic test due to suboptimal sensitivity. To overcome this limitation, a number of methodologies based on microfluidics have been developed for sorting circulating tumor cells from peripheral blood of patients with leukemia.
doi_str_mv 10.1186/s13036-022-00308-6
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_a89a46a961504ee9ad3c88ff8343e4d0</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A724837838</galeid><doaj_id>oai_doaj_org_article_a89a46a961504ee9ad3c88ff8343e4d0</doaj_id><sourcerecordid>A724837838</sourcerecordid><originalsourceid>FETCH-LOGICAL-c574t-ceb70dfa2a81f42eb0afba9b0623a8fb374feac99d1d16484a2ab428582f0a573</originalsourceid><addsrcrecordid>eNptkktv1DAQgCMEEqXwBzhF4gKHFL9iOxdQVfFYaSUkHmdr4oy3Xpy42EnF_nucblWxCPlga-bzZ3s8VfWSkgtKtXybKSdcNoSxhhBOdCMfVWdUtaKhktLHf62fVs9y3hPSdox1Z9X7LfQYGpcQ6wFntLOPUx1dHXD5iaO39XjAEPsAec61n-rrA4QlxalkwPrhefXEQcj44n4-r358_PD96nOz_fJpc3W5bWyrxNxY7BUZHDDQ1AmGPQHXQ9cTyTho13MlHILtuoEOVAotCtkLplvNHIFW8fNqc_QOEfbmJvkR0sFE8OYuENPOQJq9DWhAdyAkdJK2RCB2MHCrtXOaC45iIMX17ui6WfoRB4vTnCCcSE8zk782u3hrOsk0YbQIXt8LUvy1YJ7N6LPFEGDCuGTDFKeCrXRBX_2D7uOSplKqlVJSKFWu9UDtoDzATy6Wc-0qNZeKCc2V5qvr4j9UGcP6UXFC50v8ZMObkw2FmfH3vIMlZ7P59vWUZUfWpphzQvdQD0rM2mPm2GOm9Ji56zEj-R9fRcKN</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2737647734</pqid></control><display><type>article</type><title>Label-free detection of leukemic myeloblasts in hyaluronic acid</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Park, Suhyun ; Kim, Hyueyun ; Woo, Minna ; Kim, Minsuk</creator><creatorcontrib>Park, Suhyun ; Kim, Hyueyun ; Woo, Minna ; Kim, Minsuk</creatorcontrib><description>Chronic myeloid leukemia is generally required bone marrow biopsy for diagnosis. Although examining peripheral blood is less invasive, it has not been fully validated as a routine diagnostic test due to suboptimal sensitivity. To overcome this limitation, a number of methodologies based on microfluidics have been developed for sorting circulating tumor cells from peripheral blood of patients with leukemia.</description><identifier>ISSN: 1754-1611</identifier><identifier>EISSN: 1754-1611</identifier><identifier>DOI: 10.1186/s13036-022-00308-6</identifier><language>eng</language><publisher>London: BioMed Central Ltd</publisher><subject>Analysis ; Biopsy ; Blood ; Blood circulation ; Bone marrow ; Chronic myeloid leukemia ; Digital cameras ; Drug efficacy ; Fluctuations ; Hyaluronic acid ; Invasiveness ; Leukemia ; Methodology ; Microfluidic system ; Microfluidics ; Microscopy ; Motion microscopy ; Myeloid leukemia ; Newtonian fluids ; Non Newtonian fluids ; Peripheral blood ; Proteins ; Sensitivity analysis ; Shear stress ; Tumor cells ; Variance analysis ; Vibration ; Viscosity</subject><ispartof>Journal of biological engineering, 2022-11, Vol.16 (1), p.1-29, Article 29</ispartof><rights>COPYRIGHT 2022 BioMed Central Ltd.</rights><rights>2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c574t-ceb70dfa2a81f42eb0afba9b0623a8fb374feac99d1d16484a2ab428582f0a573</citedby><cites>FETCH-LOGICAL-c574t-ceb70dfa2a81f42eb0afba9b0623a8fb374feac99d1d16484a2ab428582f0a573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628021/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2737647734?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids></links><search><creatorcontrib>Park, Suhyun</creatorcontrib><creatorcontrib>Kim, Hyueyun</creatorcontrib><creatorcontrib>Woo, Minna</creatorcontrib><creatorcontrib>Kim, Minsuk</creatorcontrib><title>Label-free detection of leukemic myeloblasts in hyaluronic acid</title><title>Journal of biological engineering</title><description>Chronic myeloid leukemia is generally required bone marrow biopsy for diagnosis. Although examining peripheral blood is less invasive, it has not been fully validated as a routine diagnostic test due to suboptimal sensitivity. To overcome this limitation, a number of methodologies based on microfluidics have been developed for sorting circulating tumor cells from peripheral blood of patients with leukemia.</description><subject>Analysis</subject><subject>Biopsy</subject><subject>Blood</subject><subject>Blood circulation</subject><subject>Bone marrow</subject><subject>Chronic myeloid leukemia</subject><subject>Digital cameras</subject><subject>Drug efficacy</subject><subject>Fluctuations</subject><subject>Hyaluronic acid</subject><subject>Invasiveness</subject><subject>Leukemia</subject><subject>Methodology</subject><subject>Microfluidic system</subject><subject>Microfluidics</subject><subject>Microscopy</subject><subject>Motion microscopy</subject><subject>Myeloid leukemia</subject><subject>Newtonian fluids</subject><subject>Non Newtonian fluids</subject><subject>Peripheral blood</subject><subject>Proteins</subject><subject>Sensitivity analysis</subject><subject>Shear stress</subject><subject>Tumor cells</subject><subject>Variance analysis</subject><subject>Vibration</subject><subject>Viscosity</subject><issn>1754-1611</issn><issn>1754-1611</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkktv1DAQgCMEEqXwBzhF4gKHFL9iOxdQVfFYaSUkHmdr4oy3Xpy42EnF_nucblWxCPlga-bzZ3s8VfWSkgtKtXybKSdcNoSxhhBOdCMfVWdUtaKhktLHf62fVs9y3hPSdox1Z9X7LfQYGpcQ6wFntLOPUx1dHXD5iaO39XjAEPsAec61n-rrA4QlxalkwPrhefXEQcj44n4-r358_PD96nOz_fJpc3W5bWyrxNxY7BUZHDDQ1AmGPQHXQ9cTyTho13MlHILtuoEOVAotCtkLplvNHIFW8fNqc_QOEfbmJvkR0sFE8OYuENPOQJq9DWhAdyAkdJK2RCB2MHCrtXOaC45iIMX17ui6WfoRB4vTnCCcSE8zk782u3hrOsk0YbQIXt8LUvy1YJ7N6LPFEGDCuGTDFKeCrXRBX_2D7uOSplKqlVJSKFWu9UDtoDzATy6Wc-0qNZeKCc2V5qvr4j9UGcP6UXFC50v8ZMObkw2FmfH3vIMlZ7P59vWUZUfWpphzQvdQD0rM2mPm2GOm9Ji56zEj-R9fRcKN</recordid><startdate>20221101</startdate><enddate>20221101</enddate><creator>Park, Suhyun</creator><creator>Kim, Hyueyun</creator><creator>Woo, Minna</creator><creator>Kim, Minsuk</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>AAYXX</scope><scope>CITATION</scope><scope>ISR</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0S</scope><scope>M7P</scope><scope>M7S</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20221101</creationdate><title>Label-free detection of leukemic myeloblasts in hyaluronic acid</title><author>Park, Suhyun ; Kim, Hyueyun ; Woo, Minna ; Kim, Minsuk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c574t-ceb70dfa2a81f42eb0afba9b0623a8fb374feac99d1d16484a2ab428582f0a573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Analysis</topic><topic>Biopsy</topic><topic>Blood</topic><topic>Blood circulation</topic><topic>Bone marrow</topic><topic>Chronic myeloid leukemia</topic><topic>Digital cameras</topic><topic>Drug efficacy</topic><topic>Fluctuations</topic><topic>Hyaluronic acid</topic><topic>Invasiveness</topic><topic>Leukemia</topic><topic>Methodology</topic><topic>Microfluidic system</topic><topic>Microfluidics</topic><topic>Microscopy</topic><topic>Motion microscopy</topic><topic>Myeloid leukemia</topic><topic>Newtonian fluids</topic><topic>Non Newtonian fluids</topic><topic>Peripheral blood</topic><topic>Proteins</topic><topic>Sensitivity analysis</topic><topic>Shear stress</topic><topic>Tumor cells</topic><topic>Variance analysis</topic><topic>Vibration</topic><topic>Viscosity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Suhyun</creatorcontrib><creatorcontrib>Kim, Hyueyun</creatorcontrib><creatorcontrib>Woo, Minna</creatorcontrib><creatorcontrib>Kim, Minsuk</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest Biological Science Journals</collection><collection>Engineering Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Open Access: DOAJ - Directory of Open Access Journals</collection><jtitle>Journal of biological engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Suhyun</au><au>Kim, Hyueyun</au><au>Woo, Minna</au><au>Kim, Minsuk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Label-free detection of leukemic myeloblasts in hyaluronic acid</atitle><jtitle>Journal of biological engineering</jtitle><date>2022-11-01</date><risdate>2022</risdate><volume>16</volume><issue>1</issue><spage>1</spage><epage>29</epage><pages>1-29</pages><artnum>29</artnum><issn>1754-1611</issn><eissn>1754-1611</eissn><abstract>Chronic myeloid leukemia is generally required bone marrow biopsy for diagnosis. Although examining peripheral blood is less invasive, it has not been fully validated as a routine diagnostic test due to suboptimal sensitivity. To overcome this limitation, a number of methodologies based on microfluidics have been developed for sorting circulating tumor cells from peripheral blood of patients with leukemia.</abstract><cop>London</cop><pub>BioMed Central Ltd</pub><doi>10.1186/s13036-022-00308-6</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1754-1611
ispartof Journal of biological engineering, 2022-11, Vol.16 (1), p.1-29, Article 29
issn 1754-1611
1754-1611
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_a89a46a961504ee9ad3c88ff8343e4d0
source Publicly Available Content Database; PubMed Central
subjects Analysis
Biopsy
Blood
Blood circulation
Bone marrow
Chronic myeloid leukemia
Digital cameras
Drug efficacy
Fluctuations
Hyaluronic acid
Invasiveness
Leukemia
Methodology
Microfluidic system
Microfluidics
Microscopy
Motion microscopy
Myeloid leukemia
Newtonian fluids
Non Newtonian fluids
Peripheral blood
Proteins
Sensitivity analysis
Shear stress
Tumor cells
Variance analysis
Vibration
Viscosity
title Label-free detection of leukemic myeloblasts in hyaluronic acid
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T17%3A45%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Label-free%20detection%20of%20leukemic%20myeloblasts%20in%20hyaluronic%20acid&rft.jtitle=Journal%20of%20biological%20engineering&rft.au=Park,%20Suhyun&rft.date=2022-11-01&rft.volume=16&rft.issue=1&rft.spage=1&rft.epage=29&rft.pages=1-29&rft.artnum=29&rft.issn=1754-1611&rft.eissn=1754-1611&rft_id=info:doi/10.1186/s13036-022-00308-6&rft_dat=%3Cgale_doaj_%3EA724837838%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c574t-ceb70dfa2a81f42eb0afba9b0623a8fb374feac99d1d16484a2ab428582f0a573%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2737647734&rft_id=info:pmid/&rft_galeid=A724837838&rfr_iscdi=true