Clinical efficacy of toothpaste containing 8.0% arginine and calcium carbonate for teeth hypersensitivity

Abstract The prevalence of dentin hypersensitivity in Taiwan has been reported up to 38%. The aim of this study was to evaluate the clinical efficacy of desensitizing toothpaste containing 8.0% arginine and calcium carbonate in treating dentin hypersensitivity. Forty-three participants with establis...

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Bibliographic Details
Published in:Journal of dental sciences 2013-12, Vol.8 (4), p.444-447
Main Authors: Hsu, Hui-Chieh, Lee, Shiuan-Shinn, Chang, Yu-Chao
Format: Article
Language:English
Subjects:
Advanced Basic Science
arginine
calcium carbonate
dentin hypersensitivity
Dentistry
toothpaste
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Summary:Abstract The prevalence of dentin hypersensitivity in Taiwan has been reported up to 38%. The aim of this study was to evaluate the clinical efficacy of desensitizing toothpaste containing 8.0% arginine and calcium carbonate in treating dentin hypersensitivity. Forty-three participants with established two hypersensitive teeth were enrolled with informed consent. Air blast sensitivity assessments were conducted at baseline and again after four and eight weeks of twice-daily product use. The use of desensitizing toothpaste was found to significantly reduce dentin hypersensitivity (P < 0.001). The one-way analysis of variance analysis followed by Tukey's test indicated that this desensitizing toothpaste had a time-to-improvement distribution (P < 0.05). Taken together, the toothpaste containing 8.0% arginine and calcium carbonate provides a significant reduction in dentin hypersensitivity.
ISSN:1991-7902
DOI:10.1016/j.jds.2013.06.008