Association between Chronic Kidney Disease and Dynapenia in Elderly Koreans

Chronic kidney disease (CKD) is caused by various factors such as chronic inflammation, oxidative stress, and obesity. Loss of muscle strength and mass is a negative prognostic factor for CKD. Therefore, in this study, we aimed to investigate the association between CKD and dynapenia in the Korean e...

Full description

Saved in:
Bibliographic Details
Published in:Healthcare (Basel) 2023-11, Vol.11 (22), p.2976
Main Authors: Lee, Do-Youn, Shin, Sunghoon
Format: Article
Language:English
Subjects:
Aged patients
Analysis
Atrophy, Muscular
Blood pressure
Body mass index
Care and treatment
chronic kidney disease
Chronic kidney failure
Complications and side effects
Creatinine
Diagnosis
Disease control
dynapenia
Exercise
Glucose
Health surveys
Inflammation
Kidney diseases
Kidney function tests
Marital status
Mortality
Muscle strength
Nutrition
Physical fitness
Prognosis
Regression analysis
Sarcopenia
Socioeconomic factors
Surveys
Walking
Womens health
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chronic kidney disease (CKD) is caused by various factors such as chronic inflammation, oxidative stress, and obesity. Loss of muscle strength and mass is a negative prognostic factor for CKD. Therefore, in this study, we aimed to investigate the association between CKD and dynapenia in the Korean elderly. To this end, we analyzed 7029 participants from the 2014–2019 Korean National Health and Nutrition Examination Survey (KNHANES) aged ≥65 years. After adjusting for all of the covariates that could affect the results, such as physical examinations, lifestyle factors, and exercise, the association between CKD and dynapenia was found to be significant, at 1.207 (95% CI: 1.056–1.379) in CKD stage 2 and 1.790 (95% CI: 1.427–2.246) in CKD stage 3a–5. However, when sexes were analyzed separately, women were significant in both CKD stage 2 and stage 3–5 compared to normal, but only in stage 3–5 for men. Additionally, the prevalence of dynapenia increased significantly as the stage of CKD increased (normal, stage 2, and stage 3–5: 18.5%, 20.8%, and 32.3% in men and 27.5%, 34.4%, and 46.1% in women, respectively). Thus, CKD is significantly related to dynapenia, especially in women, when stratified by sex.
ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare11222976