Comparison of Vitamin D Levels, Bone Metabolic Marker Levels, and Bone Mineral Density among Patients with Thyroid Disease: A Cross-Sectional Study

Thyroid hormones have a catabolic effect on bone homeostasis. Hence, this study aimed to evaluate serum vitamin D, calcium, and phosphate and bone marker levels and bone mineral density (BMD) among patients with different thyroid diseases. This cross-sectional study included patients with underlying...

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Bibliographic Details
Published in:Diagnostics (Basel) 2020-12, Vol.10 (12), p.1075
Main Authors: Mat Ali, Masliza Hanuni, Tuan Ismail, Tuan Salwani, Wan Azman, Wan Norlina, Yaacob, Najib Majdi, Yahaya, Norhayati, Draman, Nani, Wan Mohamed, Wan Mohd Izani, Abdullah, Mohd Shafie, Ibrahim, Hanim Afzan, Wan Nik, Wan Nor Fazila Hafizan, Mohamed, Mafauzy
Format: Article
Language:English
Subjects:
Age
Bone density
bone mineral density
bone turn over markers
Clinical medicine
Committees
Cross-sectional studies
euthyroid
Fractures
Hospitals
hyperthyroid
Hyperthyroidism
hypothyroid
Hypothyroidism
Immunoassay
Laboratories
Osteoporosis
Sample size
Thyroid diseases
Variables
Variance analysis
Vitamin D
Vitamin deficiency
Womens health
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Summary:Thyroid hormones have a catabolic effect on bone homeostasis. Hence, this study aimed to evaluate serum vitamin D, calcium, and phosphate and bone marker levels and bone mineral density (BMD) among patients with different thyroid diseases. This cross-sectional study included patients with underlying thyroid diseases ( = 64, hyperthyroid; = 53 euthyroid; = 18, hypothyroid) and healthy controls ( = 64). BMD was assessed using z-score and left hip and lumbar bone density (g/cm ). The results showed that the mean serum vitamin D Levels of all groups was low (
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics10121075