Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report

An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis. Orf virus was detected by electron microscopy and viral DNA was identified by PCR. To reveal the genetic characte...

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Bibliographic Details
Published in:Virology journal 2009-10, Vol.6 (1), p.167-167, Article 167
Main Authors: Oem, Jae-Ku, Roh, In-Soon, Lee, Kyung-Hyun, Lee, Kyoung-Ki, Kim, Hye-Ryoung, Jean, Young-Hwa, Lee, O-Soo
Format: Article
Language:English
Subjects:
Animals
Case Report
Cluster Analysis
Disease Outbreaks
Diseases
DNA viruses
DNA, Viral - genetics
Ecthyma, Contagious - epidemiology
Ecthyma, Contagious - virology
Goat Diseases - epidemiology
Goat Diseases - virology
Goats
Lip - virology
Molecular evolution
Molecular Sequence Data
Orf virus - classification
Orf virus - genetics
Orf virus - isolation & purification
Phylogeny
Physiological aspects
Polymerase Chain Reaction
Properties
Republic of Korea - epidemiology
Sequence Analysis, DNA
Sequence Homology
Skin - virology
Taiwan
Viral Envelope Proteins - genetics
Virion - ultrastructure
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Summary:An outbreak of orf virus infection in dairy goats in Korea was investigated. Suspected samples of the skin and lip of affected goats were sent to the laboratory for more exact diagnosis. Orf virus was detected by electron microscopy and viral DNA was identified by PCR. To reveal the genetic characteristics of the Korean strain (ORF/09/Korea), the sequences of the major envelope protein (B2L) and orf virus interferon resistance (VIR) genes were determined and then compared with published reference sequences. Phylogenetic analysis revealed that the ORF/09/Korea strain was closest to the isolates (Taiping) from Taiwan. This is believed to be the first report on the molecular characterization of orf virus in Korea.
ISSN:1743-422X
1743-422X
DOI:10.1186/1743-422X-6-167