Recurrent podocytopathy in a patient with systemic lupus erythematosus

Podocytopathy in systemic lupus erythematosus is characterised by diffuse foot process effacement without significant peripheral capillary wall immune deposits as seen on electron microscopy. Lupus podocytopathy falls outside the scope of the current International Society of Nephrology and the Renal...

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Bibliographic Details
Published in:SAGE open medical case reports 2017-01, Vol.5, p.2050313X17695997
Main Authors: Paramalingam, Shereen, Wong, Daniel D, Dogra, Gursharan K, Nossent, Johannes C
Format: Article
Language:English
Subjects:
Case Report
Case reports
Kidney diseases
Lupus
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Summary:Podocytopathy in systemic lupus erythematosus is characterised by diffuse foot process effacement without significant peripheral capillary wall immune deposits as seen on electron microscopy. Lupus podocytopathy falls outside the scope of the current International Society of Nephrology and the Renal Pathology Society classification of lupus nephritis. We present a case of relapsing podocytopathy with nephrotic syndrome occurring simultaneously with two extra-renal and serological disease flares, which makes it likely that podocytopathy was related to systemic lupus erythematosus activity. This case adds to the growing body of evidence that lupus podocytopathy must be considered in the differential diagnosis of systemic lupus erythematosus patients presenting with nephrotic syndrome.
ISSN:2050-313X
2050-313X
DOI:10.1177/2050313X17695997