Synthesis of graphene quantum dots and their applications in drug delivery

This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-releas...

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Bibliographic Details
Published in:Journal of nanobiotechnology 2020-10, Vol.18 (1), p.142-142, Article 142
Main Authors: Zhao, Changhong, Song, Xuebin, Liu, Ya, Fu, Yifeng, Ye, Lilei, Wang, Nan, Wang, Fan, Li, Lu, Mohammadniaei, Mohsen, Zhang, Ming, Zhang, Qiqing, Liu, Johan
Format: Article
Language:English
Subjects:
Animals
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
Autophagy
Bioavailability
Biocompatibility
Bottom-up
Carbon
Chemical vapor deposition
Cytotoxicity
Delivery-release mode
Drug delivery
Drug delivery systems
Drug Delivery Systems - methods
Drug Liberation
Graphene
Graphene quantum dots
Graphite
Graphite - chemical synthesis
High temperature
Lung cancer
Magnetics
Methods
Mice
Nanomaterials
Nanoparticles
Oxidation
Oxidation-Reduction
Particle Size
pH effects
Photothermal Therapy
Quantum dots
Quantum Dots - chemistry
Review
Synthesis
Top-down
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Summary:This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.
ISSN:1477-3155
1477-3155
DOI:10.1186/s12951-020-00698-z