Aberrant Oscillatory Activity during Simple Movement in Task-Specific Focal Hand Dystonia

In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to e...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in neurology 2012, Vol.3, p.165-165
Main Authors: Hinkley, Leighton B N, Dolberg, Rebecca, Honma, Susanne, Findlay, Anne, Byl, Nancy N, Nagarajan, Srikantan S
Format: Article
Language:English
Subjects:
focal hand dystonia
Magnetoencephalography
Motor Cortex
Neuroimaging
Neuroscience
oscillations
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to elaborate the temporal and spatial characteristics of cortical activity during movement. A self-paced finger tapping task during MEG recording was performed by 11 patients with tspFHD and 11 matched healthy controls. In both groups robust changes in beta (12-30 Hz) and high gamma (65-90 Hz) oscillatory activity were identified over sensory and motor cortices during button press. A significant decrease [p 
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2012.00165