Long term adherence to continuous positive Airway pressure in mild obstructive sleep apnea

• Published in: BMC pulmonary medicine 2023-09, Vol.23 (1), p.1-320, Article 320
• Main Authors: Qiao, Min, Xie, Yiyu, Wolff, Armand, Kwon, Jeff
• Format: Article
• Language: English
• Subjects: Apnea; Body mass index; Cardiovascular disease; Care and treatment; Chi-square test; Comorbidity; Compliance; Congestive heart failure; Continuous positive airway pressure; CPAP adherence; CPAP compliance; Development and progression; Diabetes mellitus; Ethnicity; Evaluation; Gastrointestinal surgery; Home sleep apnea testing; Hospitals; Hypertension; Mechanical ventilation; Medical records; Medicine; Mild sleep apnea; Oxygen saturation; Patient compliance; Patient outcomes; Patients; Physicians; Pulmonology; Questionnaires; Respiratory tract; Sleep apnea; Sleep apnea syndromes; Sleep disorders; Software
• ISSN: 1471-2466; 1471-2466
• DOI: 10.1186/s12890-023-02612-3

Background Studies have shown that a significant percentage of patients with obstructive sleep apnea (OSA) do not tolerate continuous positive airway pressure (CPAP) therapy and long-term use may be as low as 30%. Given the lower levels of symptoms and health-related risks, patients with mild sleep apnea may be at even higher risk for non-adherence to long term CPAP. The purpose of our study was to investigate the prevalence and associations of long-term CPAP adherence in first time users with mild sleep apnea diagnosed by home sleep apnea testing (HSAT). Methods We identified all the patients who were diagnosed with mild sleep apnea (5 = < AHI < 15) by home sleep apnea testing from 01/2013 to 06/2019 at a large, combined community and hospital-based sleep practice. Only first time CPAP users were included. Compliance was defined as CPAP usage [greater than or equal to] 4 h per night on [greater than or equal to] 70% of nights over 30 consecutive days. We defined long term adherence as compliance on the 12th month following CPAP set up. Patient demographics, comorbidities, and CPAP compliance at 1st, 3rd, 6th, 9th and 12th month after therapy initiation were collected. We compared and identified the factors that had significant difference (P < 0.1) between compliant and non-compliant groups at the 12th month. Results 222 patients were included in the analysis. 57 (25.7%) patients were adherent with long term CPAP treatment. The following factors were associated with a greater likelihood for long-term CPAP adherence: older age, lower body mass index (BMI), presence of a bed partner, non-smoker, presence of Diabetes Mellitus (DM), presence of Heart Failure (CHF), lack of depression, and compliance at 1st, 3rd, 6th and 9th month. Conclusions Long term CPAP compliance in mild sleep apnea patients is low. Long term adherence to CPAP can be predicted based on CPAP adherence during the first three months. Keywords: Mild sleep apnea, CPAP compliance, CPAP adherence, Home sleep apnea testing