Correlates of insulin clearance in apparently healthy non-obese Japanese men

Hyperinsulinemia observed in obese subject is caused at least in part by low metabolic clearance rate of insulin (MCRI). However, the determinants of MCRI in non-obese subjects are not fully understood. To investigate the correlates of MCRI in healthy non-obese men (BMI

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Bibliographic Details
Published in:Scientific reports 2017-05, Vol.7 (1), p.1462-8, Article 1462
Main Authors: Kaga, Hideyoshi, Tamura, Yoshifumi, Takeno, Kageumi, Kakehi, Saori, Funayama, Takashi, Furukawa, Yasuhiko, Nishitani-Yokoyama, Miho, Shimada, Kazunori, Daida, Hiroyuki, Aoki, Shigeki, Giacca, Adria, Kanazawa, Akio, Kawamori, Ryuzo, Watada, Hirotaka
Format: Article
Language:English
Subjects:
692/163/2743/2037
692/163/2743/2815
Adipose tissue
Adipose Tissue - metabolism
Adult
Blood Glucose - metabolism
Body fat
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Fitness
Glucose
Glucose Clamp Technique
Health risks
Healthy Volunteers
Humanities and Social Sciences
Humans
Hyperinsulinemia
Hyperinsulinism - blood
Hyperinsulinism - pathology
Insulin
Insulin - blood
Insulin Resistance
Male
Metabolism
Middle Aged
multidisciplinary
Obesity - blood
Obesity - pathology
Prospective Studies
Risk factors
Science
Science (multidisciplinary)
Triglycerides - blood
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Summary:Hyperinsulinemia observed in obese subject is caused at least in part by low metabolic clearance rate of insulin (MCRI). However, the determinants of MCRI in non-obese subjects are not fully understood. To investigate the correlates of MCRI in healthy non-obese men (BMI
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-017-01469-x