Standardized immunological assays for assessing COVID-19 vaccines by the CEPI-Centralized Laboratory Network

The CEPI Centralized Laboratory Network implemented key steps in the transfer and monitoring of the developed immunological SARS-CoV-2 assays to ensure standardization across all the facilities of the network. This comprehensive evaluation reinforces the reliability of the generated data and establi...

Full description

Saved in:
Bibliographic Details
Published in:npj vaccines 2024-07, Vol.9 (1), p.128-5, Article 128
Main Authors: Azizi, Ali, Ogbeni, Deborah, Kamuyu, Gathoni, Schwartz, Lauren M., Clark, Carolyn, Spencer, Peter, Bernasconi, Valentina
Format: Article
Language:English
Subjects:
631/250/590
692/699
Antigens
Biomedical and Life Sciences
Biomedicine
Brief Communication
Clinical trials
COVID-19 vaccines
Immunology
Infectious Diseases
Laboratories
Medical Microbiology
Public Health
Quality standards
Reagents
Severe acute respiratory syndrome coronavirus 2
Software
Standardization
Vaccine
Virology
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The CEPI Centralized Laboratory Network implemented key steps in the transfer and monitoring of the developed immunological SARS-CoV-2 assays to ensure standardization across all the facilities of the network. This comprehensive evaluation reinforces the reliability of the generated data and establishes a solid foundation for a standardized approach, enabling precise inter-laboratory comparisons and contributing to the overall integrity of our network’s clinical results. Herein, we will provide a brief elaboration on the specific measures and procedures implemented to standardize the transfer of assays across our network.
ISSN:2059-0105
2059-0105
DOI:10.1038/s41541-024-00921-0