Left Ventricular Ejection Fraction Change Following Percutaneous Coronary Intervention: Correlates and Association With Prognosis

• Published in: Journal of the American Heart Association 2024-11, Vol.13 (21), p.e035791
• Main Authors: Ndrepepa, Gjin, Cassese, Salvatore, Byrne, Robert A, Bevapi, Blerina, Joner, Michael, Sager, Hendrik B, Kufner, Sebastian, Xhepa, Erion, Ibrahim, Tareq, Laugwitz, Karl-Ludwig, Schunkert, Heribert, Kastrati, Adnan
• Format: Article
• Language: English
• Subjects: Aged; Coronary Angiography; coronary artery disease; Coronary Artery Disease - diagnosis; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - mortality; Coronary Artery Disease - physiopathology; Coronary Artery Disease - therapy; death; Female; Humans; left ventricular ejection fraction; Male; Middle Aged; percutaneous coronary intervention; Percutaneous Coronary Intervention - adverse effects; Prognosis; Recovery of Function; Retrospective Studies; Risk Factors; Stroke Volume - physiology; Time Factors; Treatment Outcome; Ventricular Function, Left - physiology
• ISSN: 2047-9980; 2047-9980
• DOI: 10.1161/JAHA.124.035791

The association between left ventricular ejection fraction (LVEF) change (ΔLVEF) following percutaneous coronary intervention (PCI) and the long-term mortality rate in patients with coronary artery disease is incompletely investigated. We aimed to assess the impact of PCI on LVEF and the association of ΔLVEF after PCI with the long-term mortality rate. This observational study included 8181 patients with paired angiographic LVEF measurements performed at baseline and 6 to 8 months following the index PCI. ΔLVEF was defined as LVEF measured on the 6- to 8-month angiography minus LVEF measured on the baseline angiography. LVEF change was classified according to the following categories: reduced (ΔLVEF 0% to