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Cellulose-Sulfuric Acid as an Efficient Biosupported Catalyst in One-Pot Synthesis of Novel Heteroaryl Substituted 1,4-Dihydropyridines

An efficient method for the synthesis of new heteroaryl substituted dihydropyridine derivatives via a one-pot four-component coupling reaction of heteroaldehyde, 1,3-diketone, ethylacetoacetate, and amonium acetate in the presence of cellulose-sulfuric acid as a biosupported solid acid catalyst was...

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Bibliographic Details
Published in:Journal of chemistry 2013-01, Vol.2013 (1)
Main Authors: Mamaghani, Manouchehr, Tabatabaeian, Khalil, Mohammadi, Mohaddesseh, Khorshidi, Alireza
Format: Article
Language:English
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Summary:An efficient method for the synthesis of new heteroaryl substituted dihydropyridine derivatives via a one-pot four-component coupling reaction of heteroaldehyde, 1,3-diketone, ethylacetoacetate, and amonium acetate in the presence of cellulose-sulfuric acid as a biosupported solid acid catalyst was developed. The reaction gave the new derivatives of fused 1,4-dihydropyridines in lower reaction times and excellent yields (85–95%).
ISSN:2090-9063
2090-9071
DOI:10.1155/2013/490972