Epidemiological Study Regarding the Incidence of Venous Thromboembolism in Patients After Cancer Remission

Introduction The time course of reduction in the risk of venous thromboembolism (VTE) in patients who were diagnosed with cancer, treated with anticancer therapy, and in remission is unclear. We hypothesized that the risk of VTE will decrease over time after cancer remission. Methods We conducted a...

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Bibliographic Details
Published in:Cardiology and Therapy 2022-12, Vol.11 (4), p.611-623
Main Authors: Imura, Miki, Katada, Jun, Shiga, Taro
Format: Article
Language:English
Subjects:
Anticoagulants
Cancer regression
Cancer remission
Cardiology
Care and treatment
Deep vein thrombosis
Epidemiology
Internal Medicine
Medicine
Medicine & Public Health
Original Research
Pulmonary embolism
Statistics
Thromboembolism
Venous thromboembolism
Venous thrombosis
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Summary:Introduction The time course of reduction in the risk of venous thromboembolism (VTE) in patients who were diagnosed with cancer, treated with anticancer therapy, and in remission is unclear. We hypothesized that the risk of VTE will decrease over time after cancer remission. Methods We conducted a retrospective analysis using claims data for cancer remission in Japan. Background information of patients who developed VTE after cancer remission was collected, and the VTE incidence rate after cancer remission was analyzed. Subgroup analysis based on VTE history, cancer type, and the presence or absence of surgery during hospitalization was conducted. Results A total of 638,908 patients were eligible for the analysis. VTE occurred in 5533 of 638,908 cases, pulmonary embolism occurred in 779 cases, and deep vein thrombosis occurred in 5084 cases after cancer remission. The mean age of patients who developed VTE was 70.1 ± 12.5 years, and the proportion of men was 47.5%. All comorbidities and medications were higher in the VTE group ( P  
ISSN:2193-8261
2193-6544
DOI:10.1007/s40119-022-00285-3