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One-pot synthesis of 1,2,4,5-tetra substituted imidazoles using sulfonic acid functionalized silica (SiO2-Pr-SO3H)

SiO2-Pr-SO3H has been used as an efficient catalyst for an improved and rapid synthesis of 1,2,4,5-tetrasubstituted imidazoles, by four-component, one-pot reaction of 1,2-diketones, aryl aldehydes, ammonium acetate and substituted aromatic amines in excellent yields under solvent-free conditions.

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Bibliographic Details
Published in:Arabian journal of chemistry 2015-09, Vol.8 (5), p.692-697
Main Authors: Mohammadi Ziarani, Ghodsi, Dashtianeh, Zeinab, Shakiba Nahad, Monireh, Badiei, Alireza
Format: Article
Language:English
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Summary:SiO2-Pr-SO3H has been used as an efficient catalyst for an improved and rapid synthesis of 1,2,4,5-tetrasubstituted imidazoles, by four-component, one-pot reaction of 1,2-diketones, aryl aldehydes, ammonium acetate and substituted aromatic amines in excellent yields under solvent-free conditions.
ISSN:1878-5352
1878-5379
DOI:10.1016/j.arabjc.2013.11.020