The Role of Heme Oxygenase-1 as an Immunomodulator in Kidney Disease

The protein heme oxygenase (HO)-1 has been implicated in the regulations of multiple immunological processes. It is well known that kidney injury is affected by immune mechanisms and that various kidney-disease forms may be a result of autoimmune disease. The current study describes in detail the ro...

Full description

Saved in:
Bibliographic Details
Published in:Antioxidants 2022-12, Vol.11 (12), p.2454
Main Authors: Athanassiadou, Virginia, Plavoukou, Stella, Grapsa, Eirini, Detsika, Maria G
Format: Article
Language:English
Subjects:
Animal models
Antibodies
Autoimmune diseases
Biopsy
Blood pressure
Cytokines
Health aspects
Hematuria
Heme
heme oxygenase
Heme oxygenase (decyclizing)
HIV
Human immunodeficiency virus
Hypertension
immune injury
Immunology
Immunomodulation
Infections
Inflammation
kidney
Kidney diseases
Medical research
Microscopy
Nitric oxide
Oxidases
Oxidative stress
Oxygenase
Patients
Physiological aspects
Review
Tropical diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The protein heme oxygenase (HO)-1 has been implicated in the regulations of multiple immunological processes. It is well known that kidney injury is affected by immune mechanisms and that various kidney-disease forms may be a result of autoimmune disease. The current study describes in detail the role of HO-1 in kidney disease and provides the most recent observations of the effect of HO-1 on immune pathways and responses both in animal models of immune-mediated disease forms and in patient studies.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox11122454