Salivary Gland Scintigraphy in Patients with Sjogren’s Syndrome: A local Experience with Dual-tracer

Objective(s):To review the findings of the patients with Sjögren’s syndrome (SS) having technetium99-m-pertechnetate (99mTc-pertechnetate) and gallium67- citrate (Ga-67) salivary gland scintigraphy in the past eight years.Methods:The patients with SS, who were referred to our department for salivary...

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Bibliographic Details
Published in:Asia oceania journal of nuclear medicine and biology 2017-01, Vol.5 (1), p.56-65
Main Authors: Luk, Wing Hang, Yeung Jessie Tse Hang, Fung Eliza Po Yan, Lok Chiu Ming, Ng, Yuet Ming
Format: Article
Language:English
Subjects:
Citric acid
Gallium
Medical imaging
Nuclear medicine
Original
Parotid gland
Patients
Salivary gland
Scintigraphy
Sjogren's syndrome
Sjögren’s syndrome
Submandibular gland
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Summary:Objective(s):To review the findings of the patients with Sjögren’s syndrome (SS) having technetium99-m-pertechnetate (99mTc-pertechnetate) and gallium67- citrate (Ga-67) salivary gland scintigraphy in the past eight years.Methods:The patients with SS, who were referred to our department for salivary gland scintigraphy during January -2008December 2015 were studied using both 99mTc-pertechnetate and Ga-67 citrate scintigraphy.Results:Eighteen patients were included in the study, 17 of whom had positive findings on 99mTc-pertechnetate salivary gland scintigraphy. One patient had negative parotid glands findings on 99mTc-pertechnetate, but positive findings in Ga-67 study. Four patients had asymmetric involvement of the parotid glands, and one patient had asymmetric involvement of the submandibular glands in 99mTc-pertechnetate salivary gland scintigraphy. On the other hand, one patient had only submandibular gland involvement in the 99mTc-pertechnetate scan. Nine patients (18/9) had positive parotid gland findings on Ga-67 study. The involvements of the parotid glands were all symmetrical, except for one patient. No abnormal gallium uptake in the submandibular glands in our patients was noted.Conclusion:99mTc-pertechnetate salivary gland scintigraphy is sufficient for the assessment in the majority of patients with SS. Ga-67 scintigraphy may be a useful supplementary test, especially if the result of 99mTc-pertechnetate scintigraphy is not conclusive.
ISSN:2322-5718
2322-5726
DOI:10.22038/aojnmb.2016.8029