An improved method for the preparation of Ginsenoside Rg5 from ginseng fibrous root powder

Ginsenoside-Rg5, which is derived from high temperature-processed ginseng, exhibits beneficial health effects. In the present study, ginsenoside-Rg5 was directly and rapidly prepared through the extraction of ginseng fibrous root powder (GFRP) at atmospheric pressure. The results showed that the hig...

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Bibliographic Details
Published in:Heliyon 2019-10, Vol.5 (10), p.e02694-e02694, Article e02694
Main Authors: Guo, Dan-dan, Cheng, Le-qin, Zhang, Yue-wei, Zheng, Hong-chao, Ma, Hui-yong, Li, Ling
Format: Article
Language:English
Subjects:
atmospheric pressure
ethanol
Extraction
Ginseng fibrous root powder
Ginsenoside-Rg5
ginsenosides
Hydrochloric acid
Natural product chemistry
Natural product synthesis
Panax
Preparation
solvents
temperature
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Summary:Ginsenoside-Rg5, which is derived from high temperature-processed ginseng, exhibits beneficial health effects. In the present study, ginsenoside-Rg5 was directly and rapidly prepared through the extraction of ginseng fibrous root powder (GFRP) at atmospheric pressure. The results showed that the highest extraction yield (3.79%) was obtained under optimal conditions (extraction temperature of 85 °C, acid concentration of 0.06 mol/L, sample to solvent ratio of 1:55 g/mL and ethanol concentration of 95% after 4 h). The current method integrates the extraction of original saponins and the modification of the saponins to rare ginsenosides Rg5, which was more simpler operation, more milder preparation condition and more efficient. Natural product chemistry; Natural product synthesis, Hydrochloric acid; Ginsenoside-Rg5; Extraction; Ginseng fibrous root powder; Preparation
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2019.e02694