Return to work following laparoscopic‐assisted resection or open resection for rectal cancer: Findings from AlaCaRT—Australasian Laparoscopic Cancer of the Rectum Trial

• Published in: Cancer medicine (Malden, MA) MA), 2021-01, Vol.10 (2), p.552-562
• Main Authors: Law, Chi Kin, Brewer, Kate, Brown, Chris, Wilson, Kate, Bailey, Lisa, Hague, Wendy, Simes, John R., Stevenson, Andrew, Solomon, Michael, Morton, Rachael L.
• Format: Article
• Language: English
• Subjects: Age; Aged; Cancer; Cancer therapies; Clinical Cancer Research; clinical trial; Colorectal cancer; Employment; Employment - statistics & numerical data; Female; Follow-Up Studies; Humans; income; Labor force; Laparoscopy; Laparoscopy - mortality; Male; Metastases; Metastasis; Middle Aged; open abdomen techniques; Original Research; Prognosis; Prospective Studies; Questionnaires; Radiation therapy; rectal neoplasms; Rectal Neoplasms - pathology; Rectal Neoplasms - surgery; Rectum; return to work; Return to Work - statistics & numerical data; Sensitivity analysis; Sociodemographics; Socioeconomic factors; Surgery; Surgical outcomes; Surveys and Questionnaires; Survival Rate; Variables
• ISSN: 2045-7634; 2045-7634
• DOI: 10.1002/cam4.3623

Background Maintaining employment for adults with cancer is important, however, little is known about the impact of surgery for rectal cancer on an individual's capacity to return to work (RTW). This study aimed to determine the impact of laparoscopic vs. open resection on RTW at 12 months. Methods Analyses were undertaken among participants randomized in the Australian Laparoscopic Cancer of the Rectum Trial (ALaCaRT), with work status available at baseline (presurgery), and 12 months. Multivariable logistic regression, adjusted for sociodemographic and clinical characteristics estimated the effect of surgery on RTW in any capacity, or return to preoperative work status at 12 months. Results About 228 of 449 (51%) surviving trial participants at 12 months completed work status questionnaires; mean age was 62 years, 66% males, 117 of these received laparoscopic resection (51%). Of 228, 120 were employed at baseline (90 full‐time, 30 part‐time). Overall RTW in 120 participants in paid work at baseline was 78% (84% laparoscopic, 70% open surgery). Those employed full‐time were more likely to RTW at 12 months (OR, 3.55; 95% CI, 1.02–12.31). Those with distant metastases at baseline were less likely to RTW (OR, 0.07; 95% CI,