Optimal time period for blood glucose level evaluation after total knee arthroplasty in patients without diabetes: a prospective, observational study

Postoperative hyperglycemia has been reported to be a risk factor for postoperative infection even in patients without diabetes mellitus (DM). However, there is no standard for how long blood glucose level (BGL) monitoring should be performed after total knee arthroplasty (TKA). The purpose of this...

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Bibliographic Details
Published in:Journal of orthopaedic surgery and research 2022-02, Vol.17 (1), p.124-124, Article 124
Main Authors: Nagashima, Masaki, Takeshima, Kenichiro, Sasaki, Ryo, Aibara, Noriyuki, Aomatsu, Shuji, Otani, Toshiro, Ishii, Ken
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Arthroplasty, Replacement, Knee - adverse effects
Blood Glucose - metabolism
Blood glucose level
Blood sugar
Diabetes
Diabetes mellitus
Female
Glycated Hemoglobin A - analysis
Glycosylated hemoglobin
Health aspects
Humans
Hyperglycemia
Male
Medical research
Medicine, Experimental
Periprosthetic infection
Postoperative Period
Preoperative Period
Prospective Studies
Total knee arthroplasty
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Summary:Postoperative hyperglycemia has been reported to be a risk factor for postoperative infection even in patients without diabetes mellitus (DM). However, there is no standard for how long blood glucose level (BGL) monitoring should be performed after total knee arthroplasty (TKA). The purpose of this study was to determine the optimal time period for BGL evaluation after TKA in patients without DM. This prospective study included 132 knees of 110 patients who underwent TKA between March 2018 and July 2021 in our hospital. Fasting BGLs were measured preoperatively, at 9:00 PM on the day of surgery (DOS), and at 7:00 AM on postoperative days (PODs) 1, 2, and 3. Patients were divided into two groups with a preoperative hemoglobin A1c (HbA1c) cut-off value of 5.9%, and the BGLs on POD 1 were compared between the two groups. The BGLs were significantly higher on the DOS, POD 1, and POD 2 than preoperative levels. The BGL was significantly higher on POD 1 than at any other time point. Patients with an HbA1c ≥ 5.9% had significantly higher BGLs than those with an HbA1c 
ISSN:1749-799X
1749-799X
DOI:10.1186/s13018-022-03023-6