Association between serum netrin-1 levels and early neurological deterioration after acute ischemic stroke

Background and purposesExperimental studies demonstrated that netrin-1 (NT-1) has anti-inflammatory, tissue regeneration, and immune modulation properties. We aimed to discern the utility of NT-1 as a biomarker for assessing the risk of early neurological deterioration (END) after ischemic stroke. M...

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Bibliographic Details
Published in:Frontiers in neurology 2022-08, Vol.13, p.953557-953557
Main Authors: Chen, Zhuo, Cao, Tianli, Zhong, Xingju, Wu, Yong, Fu, Wei, Fan, Chaoli, Jiang, Yu, Zhou, Qi, Peng, Jie, Liao, Jieyu, You, Zhike, Yi, Xin, Tan, Jingyu
Format: Article
Language:English
Subjects:
acute ischemic stroke
biomarker
early neurological deterioration
netrin-1
Neurology
restricted cubic spline
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Summary:Background and purposesExperimental studies demonstrated that netrin-1 (NT-1) has anti-inflammatory, tissue regeneration, and immune modulation properties. We aimed to discern the utility of NT-1 as a biomarker for assessing the risk of early neurological deterioration (END) after ischemic stroke. MethodsThis was a prospective study enrolling ischemic stroke patients with symptoms onset
ISSN:1664-2295
1664-2295
DOI:10.3389/fneur.2022.953557