Immediate Effects of Functional Electrical Stimulation-Assisted Cycling on the Paretic Muscles of Patients With Hemiparesis After Stroke: Evidence From Electrical Impedance Myography

• Published in: Frontiers in aging neuroscience 2022-05, Vol.14, p.880221-880221
• Main Authors: Li, Le, Hu, Chengpeng, Leung, Kenry W C, Tong, Raymond K Y
• Format: Article
• Language: English
• Subjects: Ankle; Correlation analysis; cycling; Electrical impedance; electrical impedance myography (EIM); Electrical stimuli; Electrodes; functional electrical simulation (FES); Hypertrophy; Intervention; muscle; Muscle fatigue; Muscles; Neuromuscular diseases; Neuroscience; Paresis; Rehabilitation; Skeletal muscle; Skin; Spasticity; Statistical analysis; Stroke
• ISSN: 1663-4365; 1663-4365
• DOI: 10.3389/fnagi.2022.880221

Electrical impedance myography (EIM) has been applied to assess muscle health conditions in neuromuscular disorders. This study aimed to detect immediate muscle electrical impedance property alterations in lower extremity of chronic stroke survivors immediately after functional electrical stimulation (FES)-assisted cycling training. Fourteen chronic stroke survivors were recruited for the current study. EIM measurements were conducted before and immediately after 40-min FES-assisted cycling training for each subject. Four interested muscle groups [rectus femoris (RF), biceps femoris (BF), tibialis anterior (TA), and the medial head of gastrocnemius (MG)] were selected. Correlation analysis was performed to reveal a significant correlation between changes in EIM parameters and clinical scales [Fugl-Meyer Assessment of the lower extremity (FMA-LE); 6-min walking test (6MWT)]. Immediately after training, reactance ( ) and phase angle (θ) values significantly increased on the TA and MG muscles. Significant correlation was observed between value and FMA-LE scores ( = 0.649, = 0.012) at MG as well as and FMA scores of the ankle joint ( = 0.612, = 0.02). Resistance ( ) and θ were significantly correlated with 6MWT score (R-6MWT: = 0.651, = 0.012; θ-6MWT: = 0.621, = 0.018). This brief report demonstrated that EIM can reveal the intrinsic property alteration in the paretic muscle of chronic stroke survivors immediately after FES-assisted cycling training. These alterations might be related to muscle hypertrophy (i.e., increases in muscle fiber size). This brief report might aid the understanding of the mechanism of electrical stimulation-assisted exercise in improving muscle function of stroke survivors.