Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion

The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without...

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Published in:Physiological reports 2023-09, Vol.11 (17), p.e15801-n/a
Main Authors: Potolitsyna, Natalya, Parshukova, Olga, Vakhnina, Nadezhda, Alisultanova, Nadezhda, Kalikova, Lubov, Tretyakova, Anastasia, Chernykh, Alexey, Shadrina, Vera, Duryagina, Arina, Bojko, Evgeny
Format: Article
Language:English
Subjects:
Adaptation
Anaerobic threshold
Athletes
Biochemistry
Body weight
Catecholamines
Cross country skiing
Endurance
Exercise
exhaustion
Laboratory animals
lactate biochemical indices
Lactic acid
Metabolites
Nitric oxide
Original
Physical fitness
Physiology
rats
Swimming
swimming test
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Summary:The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (Tex) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, Tex > 240 min) and short swimming time (SST, Tex 
ISSN:2051-817X
DOI:10.14814/phy2.15801