Initial blood pH during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: a multicenter observational registry-based study

• Published in: Critical care (London, England) England), 2017-12, Vol.21 (1), p.322-322, Article 322
• Main Authors: Shin, Jonghwan, Lim, Yong Su, Kim, Kyuseok, Lee, Hui Jai, Lee, Se Jong, Jung, Euigi, You, Kyoung Min, Yang, Hyuk Jun, Kim, Jin Joo, Kim, Joonghee, Jo, You Hwan, Lee, Jae Hyuk, Hwang, Seong Youn
• Format: Article
• Language: English
• Subjects: Analysis; Cardiac arrest; Cardiopulmonary resuscitation; CPR (First aid); Medical research; Medicine, Experimental; Out-of-hospital cardiac arrest
• ISSN: 1364-8535; 1466-609X; 1364-8535
• DOI: 10.1186/s13054-017-1893-9

When an out-of-hospital cardiac arrest (OHCA) patient receives cardiopulmonary resuscitation (CPR) in the emergency department (ED), blood laboratory test results can be obtained by using point-of-care testing during CPR. In the present study, the relationship between blood laboratory test results during CPR and outcomes of OHCA patients was investigated. This study was a multicenter retrospective analysis of prospective registered data that included 2716 OHCA patients. Data from the EDs of three university hospitals in different areas were collected from January 2009 to December 2014. Univariate and multivariable analyses were conducted to elucidate the factors associated with survival to discharge and neurological outcomes. A final analysis was conducted by including patients who had no prehospital return of spontaneous circulation and those who underwent rapid blood laboratory examination during CPR. Overall, 2229 OHCA patients were included in the final analysis. Among them, the rate of survival to discharge and a good Cerebral Performance Categories Scale score were 14% and 4.4%, respectively. The pH level was independently related to survival to hospital discharge (adjusted OR 6.287, 95% CI 2.601-15.197; p