Renal Involvement in COVID-19: A Review of the Literature

Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting...

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Bibliographic Details
Published in:Infection and drug resistance 2021-01, Vol.14, p.895-903
Main Authors: Migliaccio, Marco Giuseppe, Di Mauro, Marco, Ricciolino, Riccardo, Spiniello, Giorgio, Carfora, Vincenzo, Verde, Nicoletta, Mottola, Filiberto Fausto, Coppola, Nicola
Format: Article
Language:English
Subjects:
acute kidney injury
Apoptosis
Coronaviruses
COVID-19
Creatinine
Cytokines
Health aspects
Hypotension
Infections
Kidney diseases
kidney injury
Kidneys
Literature reviews
Lungs
Medical prognosis
Mortality
Multiple organ dysfunction syndrome
Pathogenesis
Pneumonia
Renal function
Review
sars-cov-2
Severe acute respiratory syndrome coronavirus 2
Virus diseases
Viruses
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Summary:Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S288869