Mud-splattered fundus

The right eye showed [Figure 1]a radial streaking of retinal pigment epithelium (RPE) and a small 3 mm × 3 mm retinoblastoma (arrow) [Figure 1]b. Fluorescein angiography demonstrated prominent blockage from the streaks and slight hyperfluorescence of the mass. The "mud-splattered fundus" o...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2018-04, Vol.66 (4), p.573-573
Main Authors: Welch, R, Li, Xintong, Shields, Carol
Format: Article
Language:English
Subjects:
Albinism
Cancer
Care and treatment
Case studies
Consent
Diagnosis
Eye diseases
Ophthalmic Images
Ophthalmology
Retina
Retinoblastoma
Shields, Carol
Shields, Carol (1935-2003)
X chromosomes
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Summary:The right eye showed [Figure 1]a radial streaking of retinal pigment epithelium (RPE) and a small 3 mm × 3 mm retinoblastoma (arrow) [Figure 1]b. Fluorescein angiography demonstrated prominent blockage from the streaks and slight hyperfluorescence of the mass. The "mud-splattered fundus" occurs due to lyonization of X-chromosome and morphogenesis of RPE precursors with "pinwheeling" and "spreading" during embryogenesis, observed in carrier states of X-linked ocular albinism.
ISSN:0301-4738
1998-3689
DOI:10.4103/ijo.IJO_1003_17