Immune regulation based on sex differences in ischemic stroke pathology

Ischemic stroke is one of the world's leading causes of death and disability. It has been established that gender differences in stroke outcomes prevail, and the immune response after stroke is an important factor affecting patient outcomes. However, gender disparities lead to different immune...

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Bibliographic Details
Published in:Frontiers in immunology 2023-01, Vol.14, p.1087815-1087815
Main Authors: Niu, Pingping, Li, Liqin, Zhang, Yonggang, Su, Zhongzhou, Wang, Binghao, Liu, He, Zhang, Shehong, Qiu, Sheng, Li, Yuntao
Format: Article
Language:English
Subjects:
Brain Ischemia
cytokines
Female
Humans
immune cell
immune regulation
Immunology
Ischemic Stroke
ischemic stroke pathology
Male
Sex Characteristics
sex differences
Sex Factors
Stroke
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Summary:Ischemic stroke is one of the world's leading causes of death and disability. It has been established that gender differences in stroke outcomes prevail, and the immune response after stroke is an important factor affecting patient outcomes. However, gender disparities lead to different immune metabolic tendencies closely related to immune regulation after stroke. The present review provides a comprehensive overview of the role and mechanism of immune regulation based on sex differences in ischemic stroke pathology.
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2023.1087815