Mesoporous biophotonic carbon spheres with tunable curvature for intelligent drug delivery

Mesoporous carbon spheres (MCSs) are widely used in the field of pollutants adsorption, energy storage and various biomedicine applications such as targeted delivery vector, phototherapy sensitizers, bioimaging contrast agents, etc. Current synthetic strategies including soft templating and hard tem...

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Bibliographic Details
Published in:Nanophotonics (Berlin, Germany) Germany), 2022-12, Vol.11 (22), p.5165-5175
Main Authors: Fu, Jianye, Hui, Tiankun, An, Dong, Shan, Wei, Chen, Guobo, Wageh, Swelm, Al-Hartomy, Omar A., Zhang, Bin, Xie, Ni, Nie, Guohui, Jiao, Jinqing, Qiu, Meng, Zhang, Han
Format: Article
Language:English
Subjects:
Adsorption
biophotonic carbon spheres
Carbon
Chemistry
Collaboration
Contrast agents
Controlled release
drug delivery
Drug delivery systems
Education
Energy storage
Engineering
Laboratories
Medical imaging
NIR photoresponse
Optoelectronics
Physics
Pollutants
Polymerization
pore structure modulation
Science
Surfactants
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Summary:Mesoporous carbon spheres (MCSs) are widely used in the field of pollutants adsorption, energy storage and various biomedicine applications such as targeted delivery vector, phototherapy sensitizers, bioimaging contrast agents, etc. Current synthetic strategies including soft templating and hard templating methods generally have the limits of using expensive surfactants or lack of control over the pore structures. Therefore, the complex and uncontrollable pore structures limit its further clinical application. Herein, we proposed a new synthetic strategy to control the uniformity of pore channel arrangement in MCSs which can modulate the photonic property and the corresponding light controlled drug release property in intelligent drug delivery. The as obtained MCSs with relative uniform pore channel arrangement and long pore channels are demonstrated to have the best NIR light-induced drug release performance. This work provides not only new synthetic method to modulate pore structure characteristics and biophotonic property of MCSs, but also uniform MCSs as novel delivery platforms with advanced controlled release performance.
ISSN:2192-8606
2192-8614
2192-8614
DOI:10.1515/nanoph-2022-0523