Vogt-Koyanagi-Harada disease in a patient of chronic myeloid leukemia

This case report describes the concurrent development of Vogt-Koyanagi-Harada (VKH) disease in a 39 year old male patient of chronic myeloid leukemia (CML). The patient being reported was a known case of CML in remission with history of painless sudden loss of vision in both eyes. Cases of leukemia...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2017-05, Vol.65 (5), p.411-413
Main Authors: Chawla, Rohan, Meena, Seema, Tomar, Ankit Singh, Venkatesh, Pradeep, Vohra, Rajpal
Format: Article
Language:English
Subjects:
Adult
Brief Communications
Care and treatment
Chronic myeloid leukemia
Diagnosis
Diagnosis, Differential
Etiology
Eye disorders
Fluorescein Angiography
Fundus Oculi
Humans
imatinib
Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - complications
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - diagnosis
Male
Meningoencephalitis
Myeloid leukemia
Ophthalmology
Optics
Physiological aspects
Remission
Side effects
Steroid hormones
Tinnitus
Tomography
Tomography, Optical Coherence
Uveomeningoencephalitic Syndrome - diagnosis
Uveomeningoencephalitic Syndrome - etiology
Visual Acuity
Vogt–Koyanagi–Harada disease
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Summary:This case report describes the concurrent development of Vogt-Koyanagi-Harada (VKH) disease in a 39 year old male patient of chronic myeloid leukemia (CML). The patient being reported was a known case of CML in remission with history of painless sudden loss of vision in both eyes. Cases of leukemia can present with visual loss due to multiple ocular manifestations of leukemia itself or side effects of modern drugs used for its treatment. Clinical examination and multimodal imaging of our patient were suggestive of concurrent development of VKH. The patient was started on oral steroids, to which he showed a good response. Thus, the cases of CML may rarely develop concurrent ocular disorders not related to leukemia. These associated ocular disorders need to be distinguished from the ocular manifestations of leukemia itself. Our case highlights the concurrent development of VKH as the etiology of visual loss in a case of CML.
ISSN:0301-4738
1998-3689
DOI:10.4103/ijo.IJO_712_16