Evaluating the Relationship of Airflow Obstruction in COPD with Severity of OSA Among Patients with Overlap Syndrome

Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are common diseases affecting millions worldwide. These two diseases have a complex relationship that is not well understood. Previous small studies suggest an inverse relationship of disease severity of OSA w...

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Bibliographic Details
Published in:International journal of chronic obstructive pulmonary disease 2022-07, Vol.17, p.1613-1621
Main Authors: Stewart, Nancy H, Brittan, Mollie, McElligott, Maureen, Summers, Michael O, Samson], Kaeli, Press, Valerie G
Format: Article
Language:English
Subjects:
airflow obstruction chronic obstructive pulmonary disease obstructive sleep apnea
Lung diseases, Obstructive
Medical research
Medicine, Experimental
Original Research
Sleep apnea syndromes
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Summary:Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are common diseases affecting millions worldwide. These two diseases have a complex relationship that is not well understood. Previous small studies suggest an inverse relationship of disease severity of OSA with COPD airflow obstruction. Objective: The aim of this study was to determine if a relationship exists between severity of airflow obstruction in COPD and severity of OSA via apnea hypopnea index obtained during an in-lab baseline polysomnogram using a large quaternary care center cohort. Methods: From November 2015 through December 2018, 273 patients with confirmed COPD via spirometry and OSA via in-lab baseline polysomnogram were included. Conclusion: No associations were noted between severity of airflow obstruction in COPD and disease severity of OSA. Given the heterogeneity of these diseases, further exploration of a relationship within disease subtypes is warranted. Keywords: airflow obstruction, chronic obstructive pulmonary disease, obstructive sleep apnea
ISSN:1178-2005
1176-9106
1178-2005
DOI:10.2147/COPD.S355897